Comparason of the levels of insulin-like growth factor I (IGF-I) in aqueus fluid and serum with grades of retinopathy in patients with diabetes mellitus (CROSBI ID 670176)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Kaštelan, Snježana ; Bušić, Mladen ; Zjačić-Rotkvić, Vanja ; Krpan, Ružica ; Krpan, I ; Petek, Maja
hrvatski
Comparason of the levels of insulin-like growth factor I (IGF-I) in aqueus fluid and serum with grades of retinopathy in patients with diabetes mellitus
Aims: To determine the relationship between the stages of diabetic retinopathy (DR) and the levels of insulin-like growth factor I (IGF-I) in aqueous fluid and serum. Methods: Levels of the IGF-I in serum and aqueous humour obtained during cataract surgery were measured by radioimmuno assay coated tubes (RIA-CT) in 28 diabetic patients with 10 non-diabetic patients (NDM) as controls. The patients with diabetes were classified into three groups according to the stage of DR: no DR (NDR ; 10 cases), non-proliferative DR (NPDR ; 10 cases), and proliferative DR (PDR ; 8 cases). Results: No significant differences were found between any of the groups in serum concentration of IGF-I. The aqueous IGF-I levels increased with the stage of DR Conclusion. The result of our study suggests that IGF-I localy present in the ocular tissues may play roles in the progression of diabetic retinopathy.
diabetic retinopathy, insulin-like growth factor I, aqueous fluid, serum, concentration
nije evidentirano
engleski
Comparason of the levels of insulin-like growth factor I (IGF-I) in aqueus fluid and serum with grades of retinopathy in patients with diabetes mellitus
Aims: To determine the relationship between the stages of diabetic retinopathy (DR) and the levels of insulin-like growth factor I (IGF-I) in aqueous fluid and serum. Methods: Levels of the IGF-I in serum and aqueous humour obtained during cataract surgery were measured by radioimmuno assay coated tubes (RIA-CT) in 28 diabetic patients with 10 non-diabetic patients (NDM) as controls. The patients with diabetes were classified into three groups according to the stage of DR: no DR (NDR ; 10 cases), non-proliferative DR (NPDR ; 10 cases), and proliferative DR (PDR ; 8 cases). Results: No significant differences were found between any of the groups in serum concentration of IGF-I. The aqueous IGF-I levels increased with the stage of DR Conclusion. The result of our study suggests that IGF-I localy present in the ocular tissues may play roles in the progression of diabetic retinopathy.
diabetic retinopathy, insulin-like growth factor I, aqueous fluid, serum, concentration
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
23-23.
2003.
objavljeno
Podaci o matičnoj publikaciji
3. Kongres Hrvatskog oftalmološkog društva s međunarodnim sudjelovanjem.
Podaci o skupu
3. kongres Hrvatskog oftalmološkog društva s međunarodnim sudjelovanjem
predavanje
15.05.2003-17.05.2003
Rovinj, Hrvatska
