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Chondromyxoid fibroma of the mandible in an older adult: A case report

Chondromyxoid fibroma (CMF) is a rare benign neoplasm of cartilaginous origin and represents less than 1% of all primary tumors of bone. The craniofacial region is affected in only 2% of cases. CMF of the jaw is exceedingly rare, with no significant sex predilection and an average age at diagnosis of 28 (range 9–67 years). A 50 year old woman was referred by her general dentist to our department in June 2017 with a swelling in the vestibular area of the left mandible. She had first noticed this painless, slow-growing, palpable mass 6 months earlier, but had not any difficulties in everyday functioning. Extra-oral examination revealed an oval, firm, and immobile mass, measuring approximately 3.0 x 2.0 cm that was attached to the lower border of the left mandible. An incisional biopsy of the mass was performed under local infiltration anesthesia and sent for histopathologic examination, and was reported as CMF. Given that the lesion was relatively small, it was treated by conservative local enucleation via an intraoral approach. CMF is rarely located in the maxillofacial region, but should be included in the differential diagnosis in patients with a tumor affecting the skull bones because it could be misdiagnosed as one of the more aggressive tumors found in this area. A preoperative radiologic diagnosis that is concordant with the histopathologic examination is very important for surgical planning and prognostication. Using an adequate treatment modality a better outcome can be achieved with detailed knowledge of this lesion.

Chondromyxoid fibroma ; Enucleation ; Mandible ; Tumor

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