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Pregled bibliografske jedinice broj: 970659

Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S


Paradžik, Mladen; Humphries, Jonathan D.; Nestić, Davor; Majhen, Dragomira; Dekanić, Ana; Stojanović, Nikolina; Sedda, Delphine; Samaržija, Ivana; Weber, Igor; Humphries, Martin J.; Ambriović-Ristov, Andreja
Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S // Signal Transduction in Cancer : Abstract book / Defilippi, Paola ; Lanzetti, Letizia ; Belletti, Barbara (ur.).
Torino: Associazione di Biologia Cellulare e del Differenziamento, 2018. str. 5-5 (predavanje, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 970659 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S

Autori
Paradžik, Mladen ; Humphries, Jonathan D. ; Nestić, Davor ; Majhen, Dragomira ; Dekanić, Ana ; Stojanović, Nikolina ; Sedda, Delphine ; Samaržija, Ivana ; Weber, Igor ; Humphries, Martin J. ; Ambriović-Ristov, Andreja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Signal Transduction in Cancer : Abstract book / Defilippi, Paola ; Lanzetti, Letizia ; Belletti, Barbara - Torino : Associazione di Biologia Cellulare e del Differenziamento, 2018, 5-5

Skup
Associazione di Biologia Cellulare e del Differenziamento Meeting "Signal Transduction in Cancer"

Mjesto i datum
Torino, Italija, 22-24.11.2018

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
breast cancer ; melanoma ; integrins ; adhesome

Sažetak
Integrins are heterodimeric glycoproteins that bind cells to extracellular matrix proteins. Upon integrin clustering, multimolecular integrin adhesion complexes (IACs) are formed, facilitating the linkage between integrins and the actin cytoskeleton and permitting bidirectional signalling. The aim of this work was to assess αV-dependent changes in IAC composition in MDA-MB-435S melanoma cells in order to better understand the alteration of sensitivity to antitumor drugs and migration, observed upon transient transfection with integrin αV siRNA.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekti:
IP-2013-11-2465 - Molekularni mehanizmi povećanja osjetljivosti na protutumorske lijekove stanica karcinoma dojke i melanoma čovjeka utišavanjem integrina (INSILCELL) (Ambriović Ristov, Andreja, HRZZ - 2013-11) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb


Citiraj ovu publikaciju:

Paradžik, Mladen; Humphries, Jonathan D.; Nestić, Davor; Majhen, Dragomira; Dekanić, Ana; Stojanović, Nikolina; Sedda, Delphine; Samaržija, Ivana; Weber, Igor; Humphries, Martin J.; Ambriović-Ristov, Andreja
Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S // Signal Transduction in Cancer : Abstract book / Defilippi, Paola ; Lanzetti, Letizia ; Belletti, Barbara (ur.).
Torino: Associazione di Biologia Cellulare e del Differenziamento, 2018. str. 5-5 (predavanje, međunarodna recenzija, sažetak, znanstveni)
Paradžik, M., Humphries, J., Nestić, D., Majhen, D., Dekanić, A., Stojanović, N., Sedda, D., Samaržija, I., Weber, I., Humphries, M. & Ambriović-Ristov, A. (2018) Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S. U: Defilippi, P., Lanzetti, L. & Belletti, B. (ur.)Signal Transduction in Cancer : Abstract book.
@article{article, author = {Parad\v{z}ik, Mladen and Humphries, Jonathan D. and Nesti\'{c}, Davor and Majhen, Dragomira and Dekani\'{c}, Ana and Stojanovi\'{c}, Nikolina and Sedda, Delphine and Samar\v{z}ija, Ivana and Weber, Igor and Humphries, Martin J. and Ambriovi\'{c}-Ristov, Andreja}, year = {2018}, pages = {5-5}, keywords = {breast cancer, melanoma, integrins, adhesome}, title = {Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S}, keyword = {breast cancer, melanoma, integrins, adhesome}, publisher = {Associazione di Biologia Cellulare e del Differenziamento}, publisherplace = {Torino, Italija} }
@article{article, author = {Parad\v{z}ik, Mladen and Humphries, Jonathan D. and Nesti\'{c}, Davor and Majhen, Dragomira and Dekani\'{c}, Ana and Stojanovi\'{c}, Nikolina and Sedda, Delphine and Samar\v{z}ija, Ivana and Weber, Igor and Humphries, Martin J. and Ambriovi\'{c}-Ristov, Andreja}, year = {2018}, pages = {5-5}, keywords = {breast cancer, melanoma, integrins, adhesome}, title = {Characterisation of integrin αV-dependent adhesome in melanoma cell line MDA-MB-435S}, keyword = {breast cancer, melanoma, integrins, adhesome}, publisher = {Associazione di Biologia Cellulare e del Differenziamento}, publisherplace = {Torino, Italija} }




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