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Pregled bibliografske jedinice broj: 968405

Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation


Jagić, Mateja; Škiljaica, Andreja; Bauer, Nataša; Leljak-Levanić, Dunja
Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation // BOOK OF ABSTRACTS OF THE 13th CROATIAN BIOLOGICAL CONGRESS / Kružić, Petar ; Caput Mihalić, Katarina ; Gottstein, Sanja ; Pavoković, Dubravko ; Kučinić, Mladen (ur.).
Zagreb: Croatian Biological Society, 2018. str. 54-55 (predavanje, domaća recenzija, sažetak, znanstveni)


CROSBI ID: 968405 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation

Autori
Jagić, Mateja ; Škiljaica, Andreja ; Bauer, Nataša ; Leljak-Levanić, Dunja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
BOOK OF ABSTRACTS OF THE 13th CROATIAN BIOLOGICAL CONGRESS / Kružić, Petar ; Caput Mihalić, Katarina ; Gottstein, Sanja ; Pavoković, Dubravko ; Kučinić, Mladen - Zagreb : Croatian Biological Society, 2018, 54-55

Skup
13th CROATIAN BIOLOGICAL CONGRESS

Mjesto i datum
Poreč, Hrvatska, 19-23.09.2018

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
MATH-BTB, Arabidopsis thaliana, protein-protein interactions, RNA-directed DNA methylation

Sažetak
Arapidopsis BPM proteins belong to MATH-BTB protein family. MATH-BTB proteins partake in many developmental processes in plants and animals and are known as key regulators of the cell cycle. Arabidopsis genome contains six genes encoding for BPM proteins (BPM1-6). BPM proteins bind members of several transcription factor families targeting them for ubiquitination by Cullin3 E3 ligase. Our preliminary results showed BPM1 interaction with DMS3 and RDM1, important components of RNA-directed DNA methylation (RdDM). Still, the role of BPM proteins in DNA methylation remains unknown. To elucidate an involvement of other Arabidopsis MATH-BTB proteins (BPM2-6) in RdDM, interactions with DMS3 and RDM1 were examined in yeast two hybrid system. Additionally, truncated versions of the BPM1 missing an individual domain were used to test domain specificity for interaction with DMS3 and RDM1. All BPM proteins show interactions with both investigated components of RdDM. BTB domain of BPM1 protein proved to be the most important for interaction with RDM1. Results obtained here point to a role of BPM proteins in regulation of DNA methylation that will be further investigated.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekti:
HRZZ-IP-2016-06-6229 - MATH-BTB proteini kao regulatori transkripcije i RNA posredovane metilacije DNA u biljnom razvitku (PHYTOMETHDEV) (Leljak-Levanić, Dunja, HRZZ - 2016-06) ( POIROT)

Ustanove:
Prirodoslovno-matematički fakultet, Zagreb


Citiraj ovu publikaciju:

Jagić, Mateja; Škiljaica, Andreja; Bauer, Nataša; Leljak-Levanić, Dunja
Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation // BOOK OF ABSTRACTS OF THE 13th CROATIAN BIOLOGICAL CONGRESS / Kružić, Petar ; Caput Mihalić, Katarina ; Gottstein, Sanja ; Pavoković, Dubravko ; Kučinić, Mladen (ur.).
Zagreb: Croatian Biological Society, 2018. str. 54-55 (predavanje, domaća recenzija, sažetak, znanstveni)
Jagić, M., Škiljaica, A., Bauer, N. & Leljak-Levanić, D. (2018) Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation. U: Kružić, P., Caput Mihalić, K., Gottstein, S., Pavoković, D. & Kučinić, M. (ur.)BOOK OF ABSTRACTS OF THE 13th CROATIAN BIOLOGICAL CONGRESS.
@article{article, author = {Jagi\'{c}, Mateja and \v{S}kiljaica, Andreja and Bauer, Nata\v{s}a and Leljak-Levani\'{c}, Dunja}, year = {2018}, pages = {54-55}, keywords = {MATH-BTB, Arabidopsis thaliana, protein-protein interactions, RNA-directed DNA methylation}, title = {Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation}, keyword = {MATH-BTB, Arabidopsis thaliana, protein-protein interactions, RNA-directed DNA methylation}, publisher = {Croatian Biological Society}, publisherplace = {Pore\v{c}, Hrvatska} }
@article{article, author = {Jagi\'{c}, Mateja and \v{S}kiljaica, Andreja and Bauer, Nata\v{s}a and Leljak-Levani\'{c}, Dunja}, year = {2018}, pages = {54-55}, keywords = {MATH-BTB, Arabidopsis thaliana, protein-protein interactions, RNA-directed DNA methylation}, title = {Arabidopsis MATH-BTB proteins are involved in RNA- directed DNA methylation}, keyword = {MATH-BTB, Arabidopsis thaliana, protein-protein interactions, RNA-directed DNA methylation}, publisher = {Croatian Biological Society}, publisherplace = {Pore\v{c}, Hrvatska} }




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