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Pregled bibliografske jedinice broj: 966448

Značaj Ki-67 kod karcinoma glave i vrata: Pregledni rad


Žužul, Ivona; Granić , Marko; Kuna , Tihomir; Kotarac Knežević , Ana; Andabak Rogulj , Ana
Značaj Ki-67 kod karcinoma glave i vrata: Pregledni rad // Research Journal of Pharmaceutical, Biological and Chemical Sciences, 9 (2018), 6; 34-38 (međunarodna recenzija, članak, stručni)


Naslov
Značaj Ki-67 kod karcinoma glave i vrata: Pregledni rad
(The Significance of Ki-67 in Head and Neck Cancers: Review Article.)

Autori
Žužul, Ivona ; Granić , Marko ; Kuna , Tihomir ; Kotarac Knežević , Ana ; Andabak Rogulj , Ana

Izvornik
Research Journal of Pharmaceutical, Biological and Chemical Sciences (0975-8585) 9 (2018), 6; 34-38

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Ki-67 ; karcinom glave i vrata ; molekularni marker ; prognoza
(Ki-67 ; head and neck cancer ; molecular marker ; prognosis)

Sažetak
Widely accepted prognostic factors like lymph node status, tumor size and cell differentiation sometimes are not useful in oral cancer diagnostics and prognosis. Therefore, study of tumor heterogeneity which involves also molecular markers might be useful in order to explain mechanisms of appearance and recurrences of oral squamous cell cancer. The aim of the present study was to search published literature in the last 25 years regarding the role of Ki-67 in the head and neck cancers. Thirty seven articles were included and results showed that Ki-67 is not reliable prognostic marker for oral squamous cell carcinoma because of contradictory results of the available studies.

Izvorni jezik
Hrvatski

Znanstvena područja
Dentalna medicina



POVEZANOST RADA


Ustanove
Stomatološki fakultet, Zagreb