Comparative genomics of human rubulavirus 2 (CROSBI ID 255873)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Šantak, Maja ; Mlinarić-Galinović, Gordana ; Vilibić-Čavlek, Tatjana ; Tabain, Irena
engleski
Comparative genomics of human rubulavirus 2
Although human rubulavirus 2 (HPIV2) is an important respiratory pathogen, little is known about its molecular epidemiology. We performed a comparative analysis of the full-length genomes of fourteen HPIV2 isolates belonging to different genotypes. Additionally, evolutionary analyses (phylogenetic reconstruction, sequence identity, detection of recombination and adaptive evolution) were conducted. Our study presents a systematic comparative genetic analysis that complements prior analyses and utilizes full-length HPIV2 genomes to provide a basis for future work on the clinical significance, molecular variation and conservation, and evolution of HPIV2.
human parainfluenza virus type 2 ; whole genome ; conserved regions ; variable regions ; synonymous substitutions ; non-synonymous substitutions
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Podaci o izdanju
163 (11)
2018.
3141-3148
objavljeno
0304-8608
1432-8798
10.1007/s00705-018-3986-4
Povezanost rada
Biologija, Javno zdravstvo i zdravstvena zaštita, Temeljne medicinske znanosti