engleski

Diagnostic test in childreen with postive prick test on home dust

Introduction: Allergies are on the rise today. Besides the fact that allergy tests are present in daily practice, allergy diagnosis is still complicated considering that there is no unique and exact test for hipersensitivity proof. The aim of our work is to test the values of daily laboratory diagnostics tests on a group of children with hipersensitivity to house dust. Patients and Methods: A prospective test was performed in the Department of pediatrics, Zadar General Hospital which consisted of 64 children suffering from asthma and other allergy diseases with hypersensitivity in prick test on house dust and maggots. A detailed family and personal history was taken from all the children, clinical exam performed, objective lung spirometry measurement in children older than seven years and skin testing. All examinees were tested by the method of pricking the volar part of the forearm with allergen drops. Total and specific IgE antibodies were established, the number of eosinophilic granulocytes in peripheral blood, Dunger test, cytological swabs of the nose mucuous membrane and serum eosinophile cation protein. Statistical data processing was performed on a PC, and the values P < 0.01 were considered statistically significant. Results: The children were from 4 to 15 years of age: among the 64 children 39 (61%) were of male gender, while 25 children (39%) were of female gender. The family history was positive on allergies with 28 (44%) of the sick children. Besides house dust and maggots, 24 of the 64 (37%) patients proved hipersensitive to one or more pollen allergens. Most of the patients had clinical symptoms of rhinitis or rhinitis combined with conjunctivitis. Most of the afflicted children live in an urban environment. An increased number of eosinophiles in the cytological swab of nose mucuous membrane, ImmunoCAP Total IgE and UniCAP test ( P < 0.01) were statistically significant proof of hipersensitivity to house dust and maggots with afflicted children. Conclusion: Three out of six laboratory tests have shown high particularity in confirming allergy with patients that are hypersensitive to house dust. All three aforesaid tests are inevitable in the daily work with atopists.

hipersensitivity ; diagnostic tests ; childreen ; home dust

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