Purification Processes Of Xenogeneic Bone Substitutes And Their Impact On Tissue Reactions And Regeneration (CROSBI ID 666018)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Perić Kačarević, Željka ; Kavehei, Faraz ; Jung, Ole ; Smeets, Ralf ; Rimashevskiy, Denis ; Wenisch, Sabine ; Schnettler Reinhard ; Barbeck, Mike
engleski
Purification Processes Of Xenogeneic Bone Substitutes And Their Impact On Tissue Reactions And Regeneration
Xenogeneic bone substitute materials are widely used in oral implantology. Prior to their clinical use, a purification of the former bone tissue has to be conducted to ensure the removal of immunogenic components and pathogens. Different physicochemical methods are applied for the purification of the donor tissue and temperature treatment is one of these methods. Differences in these methods and especially the application of different temperatures for purification may lead to different material characteristics, which may influence the tissue reactions to these materials and the related (bone) healing process. However, little is known about the different material characteristics and their influences on the healing process. Thus, the aim of the present mini-review is to summarize the preparation processes and the related material characteristics, the safety aspects, the tissue reactions, the resorbability and the preclinical and clinical data oftwo widely used xenogeneic bone substitutes that mainly differ in the temperature treatment, i.e., sintered (cerabone) and non-sintered (Bio-Oss) bovinebone materials (BBM). Based on the summarized data from the literature a connection between the materialinduced tissue reactions and the consequences for the healing processes are presented with the aim for translation into their clinical application.
Bone substitute, xenograft, multinucleated giant cells, implant bed vascularization, inflammation
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Podaci o prilogu
486-631.
2018.
objavljeno
10.1177/0391398818785526
Podaci o matičnoj publikaciji
The International Journal of Artificial Organs
Podaci o skupu
45th ESAO Congress
poster
12.09.2018-15.09.2018
Madrid, Španjolska
Povezanost rada
Temeljne medicinske znanosti