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Pregled bibliografske jedinice broj: 955427

Salivary cortisol and antioxidan levels in patients with chronic temporomanidbular disorders


Vrbanović, Ema; Lapić, Ivana, Rogić, Dunja; Alajbeg, Iva
Salivary cortisol and antioxidan levels in patients with chronic temporomanidbular disorders // Acta stomatol Croat. 2018 ; 52(2):162-171. / Tarle, Zrinka ; Klarić, Eva (ur.).
Zagreb, 2018. str. 163-163 (poster, recenziran, sažetak, znanstveni)


Naslov
Salivary cortisol and antioxidan levels in patients with chronic temporomanidbular disorders

Autori
Vrbanović, Ema ; Lapić, Ivana, Rogić, Dunja ; Alajbeg, Iva

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Acta stomatol Croat. 2018 ; 52(2):162-171. / Tarle, Zrinka ; Klarić, Eva - Zagreb, 2018, 163-163

Skup
4th International Congress of School of Dental Medicine

Mjesto i datum
Zagreb, Hrvatska, 02-03.03.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Recenziran

Ključne riječi
Temporomandibularni poremećaji, oksidativni stres, salivarna dijagnostika, antioksidansi, salivarni kortizol
(Temporomandibular disorders, oxidative stress, salivary diagnostics, antioxidants, salivary cortisol)

Sažetak
Aim: Risk factors associated with temporomandibular disorders (TMD) include mechanical and psychological stressors that increase the likelihood of developing and maintaining a chronic pathologic state. The aim of this study was to investigate the relationship between salivary antioxidant parameters, salivary cortisol and TMD. Materials and Methods: In total, 12 patients, who were diagnosed with chronic TMD, and 15 systemically and periodontally healthy individuals were included. Five milliliters of whole unstimulated saliva was collected into a graduated tube at 2 time intervals, 7 AM and 5 PM. Salivary anti-oxidant enzymes (superoxide dismutase (SOD), and glutathione peroxidase (GPx)), total antioxidant capacity (TAC) and uric acid (UA) were analyzed using spectrophotometric methods. Salivary cortisol was determined by enzyme-linked immunosorbent assay (ELISA). T- test was used to compare salivary biomarker levels between patients with TMD and the control group. Pearson’s correlation analysis was used to study the correlation among antioxidants and salivary cortisol levels. P< 0.05 was considered significant. Results: No significant difference in age between groups was found (p>0.05). Significant differences in the mean salivary levels of SOD (p<0.001) between the groups were found whereas the mean salivary levels of cortisol, GPx, TAC and UA were higher in the TMD group but without statistical significance. There was a highly significant positive correlation (p<0.05) between salivary cortisol levels and antioxidant parameters in TMD patients. Conclusion: Previous studies showed lower levels of anti-oxidant enzymes in TMD patients indicating that anti- oxidant defense is lowered in these patients. Higher levels of antioxidants in TMD patients, as compared to healthy controls, obtained in our study, could represent compensatory increase as a result of potentially higher level of stress.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2014-09-3070 - Uloga oksidativnog stresa i opiorfina u temporomandibularnim poremećajima

Ustanove
Stomatološki fakultet, Zagreb

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)