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Rotaviruses in Croatian Ecosystem: molecular epidemiology and zoonotic potential - Reco (CROSBI ID 664723)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Brnić, Dragan ; Šimić, Ivana ; Krešić, Nina ; Škoko, Ines ; Lojkić, Ivana Rotaviruses in Croatian Ecosystem: molecular epidemiology and zoonotic potential - Reco // Power of Viruses Book of Abstracts / Bielen, Ana ; Ježić, Marin ; Jurak, Igor et al. (ur.). Zagreb: Hrvatsko mikrobiološko društvo, 2018. str. 47-47

Podaci o odgovornosti

Brnić, Dragan ; Šimić, Ivana ; Krešić, Nina ; Škoko, Ines ; Lojkić, Ivana

engleski

Rotaviruses in Croatian Ecosystem: molecular epidemiology and zoonotic potential - Reco

Rotaviruses, especially the species Rotavirus A (RVA), are worldwide distributed enteric pathogens with high prevalence and pathogenicity in humans and variety of animals. The evidence for frequent intersections between the evolution of human and animal rotaviruses has been well documented. However the research on animal RVA strains is significantly lagging, especially on strains originating in wildlife. Herein we are presenting a project that will tackle this issue with an overall aim to conduct a synchronized spatiotemporal molecular epidemiology study in order to assess the zoonotic potential of autochthonous RVA in Croatian ecosystem, by following the One Health concept. Our multidisciplinary research idea brings integrity and comprehensiveness in its approach and such concerted effort at the interface of veterinary medicine and public health is considered as warranted. By means of selected methodology, we will have a unique opportunity to get a closer look into genomic structure, genotype constellation, phylogenetic relatedness and zoonotic potential of Croatian autochthonous RVA strains simultaneously detected in domestic and wild animals, humans and environment. Moreover, the NGS technology applied for RVA whole genome sequencing will additionally reveal the diversity of viral metagenomes present in Croatian ecosystem and potentially expose new viral threats of public health importance. This study will be the first one defining a genetic backbone of RVAs in several wildlife species and bring a novel perspective on RVA evolution and the capacity of wildlife RVAs for the emergence into human and domestic animal populations. An autochthonous RVA virus bank will be formed, along with databases enabling future seamless genetic tracking of novel emerging zoonotic strains. This project will install a REco research group with the aim to boost knowledge, networking and competitiveness of each team member in the European Research Area, resulting in future novel collaborative research initiatives.

Rotavirus, Ecosystem, Croatia, Research Project

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Podaci o prilogu

47-47.

2018.

objavljeno

Podaci o matičnoj publikaciji

Power of Viruses Book of Abstracts

Bielen, Ana ; Ježić, Marin ; Jurak, Igor ; Škorić, Dijana ; Tomaić, Vjekoslav

Zagreb: Hrvatsko mikrobiološko društvo

978-953-7778-15-6

Podaci o skupu

The conference Power of Viruses

poster

16.05.2018-18.05.2018

Poreč, Hrvatska

Povezanost rada

Veterinarska medicina