hrvatski

Nekrotizirajući leukoencefalitis pasa

Nekrotizirajući leukoencefalitis je bolest nepoznata uzroka koja najčešće zahvaća male pasmine poput čivave, bostonskog i jorkširskog terijera. Klinička je slika povezana s oštećenjem mozga te uključuje grčeve, nekontrolirane pokrete i tremore. Makroskopski nalaz može biti negativan u nekih pasa, dok kod drugih varira od blage do jake nekroze i upale bijele moždane tvari (leukoencefalitis). Mikroskopski nalaz odgovara nekrotičnoj upali s limfocitno-histiocitnim perivaskularnim infiltratom koji ponajprije zahvaća bijelu tvar. Ovaj članak prikazuje slučaj nekrotičnog leukoencefalitisa u trogodišnje kuje pasmine čiuvava s opisom kliničke slike te prikazom makroskopskih i histoloških lezija u velikom mozgu.

nekrotizirajući leukoencefalitis, pas, čivava, makroskopski nalaz, histološki nalaz

Abstract Necrotizing leukoencephalitis is a disease of unknown cause, which mostly affects small dog breeds including Chihuahuas, and Boston and Yorkshire terriers. Symptoms are related to central nervous system damage and include spasms, involuntary movements and tremors. Gross findings may be absent in some dogs, while others show mild to severe necrotizing inflammation of the cerebral white matter (leukoencephalitis). Microscopic findings correspond to necrotic inflammation with lymphocytic and histiocytic cuffs primarily around the blood vessels of the white matter. This article describes a case of necrotizing leukoencephalitis in a three-year old Chihuahua bitch, with a detailed description of gross and histological cerebral lesions.