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Pregled bibliografske jedinice broj: 945474

Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome


Muhaxheri, G.; Vučićević Boras, V.; Fučić, A.; Plavec, D.; Šekerija, M.; Filipović, M.; Gršić, K.; Stubljar, B.; Krnić, T.; Vrdoljak, B.
Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome // International journal of oral and maxillofacial surgery, 47 (2018), 8; 965-970 doi:10.1016/j.ijom.2018.02.011 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 945474 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome

Autori
Muhaxheri, G. ; Vučićević Boras, V. ; Fučić, A. ; Plavec, D. ; Šekerija, M. ; Filipović, M. ; Gršić, K. ; Stubljar, B. ; Krnić, T. ; Vrdoljak, B.

Izvornik
International journal of oral and maxillofacial surgery (0901-5027) 47 (2018), 8; 965-970

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neutrofili ; omjer neutrofila i limfocita ; planocelularni karcinomi glave i vrata
(neutrophils ; neutrophil-to-lymphocyte ratio ; HNSCC)

Sažetak
Recent publications have highlighted a greater utility of routine blood tests in patients with various cancers than previously assumed. It appears that the neutrophilto-lymphocyte ratio (NLR) may be a good predictive biomarker for overall survival (OS) and disease-free survival (DFS). Preoperative and postoperative NLR data for patients with head and neck cancers have yet to be established. The aim of this study was to evaluate the preoperative and postoperative NLR in 182 patients with head and neck squamous cell carcinoma and to determine the association of NLR with OS and DFS. The statistical analysis of OS and DFS and their predictors was performed using Kaplan–Meier survival analysis and multivariate Cox proportional hazards regression analysis, with factors including age, sex, alcohol and tobacco use, tumour location, treatment after surgery, and lymphocyte and neutrophil counts. Longer OS was significantly associated with not consuming alcohol, preoperative neutrophil and lymphocyte counts, preoperative NLR, and the difference between the preoperative and postoperative NLR (P = 0.016). Longer DFS was significantly associated with not consuming alcohol, preoperative neutrophil and lymphocyte counts, postoperative NLR, and the difference between preoperative and postoperative NLR (P = 0.028).

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Stomatološki fakultet, Zagreb,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Sveučilište Libertas

Citiraj ovu publikaciju

Muhaxheri, G.; Vučićević Boras, V.; Fučić, A.; Plavec, D.; Šekerija, M.; Filipović, M.; Gršić, K.; Stubljar, B.; Krnić, T.; Vrdoljak, B.
Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome // International journal of oral and maxillofacial surgery, 47 (2018), 8; 965-970 doi:10.1016/j.ijom.2018.02.011 (međunarodna recenzija, članak, znanstveni)
Muhaxheri, G., Vučićević Boras, V., Fučić, A., Plavec, D., Šekerija, M., Filipović, M., Gršić, K., Stubljar, B., Krnić, T. & Vrdoljak, B. (2018) Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome. International journal of oral and maxillofacial surgery, 47 (8), 965-970 doi:10.1016/j.ijom.2018.02.011.
@article{article, year = {2018}, pages = {965-970}, DOI = {10.1016/j.ijom.2018.02.011}, keywords = {neutrophils, neutrophil-to-lymphocyte ratio, HNSCC}, journal = {International journal of oral and maxillofacial surgery}, doi = {10.1016/j.ijom.2018.02.011}, volume = {47}, number = {8}, issn = {0901-5027}, title = {Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome}, keyword = {neutrophils, neutrophil-to-lymphocyte ratio, HNSCC} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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