engleski

Synthesis and biological activity of new heterocyclic amidines

Amidino-substituted amides exhibit various biological activities, among others anti-cancer and anti-bacterial activity. Therefore, we prepared some new benzoamidino substituted amides of pyridine series by multistep synthesis, using Pinner reaction to convert cyano to amidino group. Biological activities of some of the prepared compounds were determined. In order to improve biological activities all the prepared compounds were methylated on pyridine nucleus using methyl-iodide.

amidines; amides; biological activity

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