engleski

Isotonic Seawater Solution as Daily Nasal Irrigation in Chronic Rhinosinuitis

Aims. Nasal obstruction, increased nasal discharge, cough and other symptoms negatively affect quality of life of chronic rhinosinusitis patients. Add on therapy with saline nasal irrigation has shown numerous benefits by improving clinical symptoms. Some clinicians prefer use of isotonic seawater solutions. It contains many minerals essential to the body fighting chronic inflammation. The present study assessed the clinical efficacy of Sterimar isotonic seawater solution in chronic rhinosinusitis patients. Methods. 30 chronic rhinosinusitis patients were enrolled in the open clinical study. Inclusion criteria were presence of congestion, nasal discharge and other symptoms of chronic inflammation. As adjuvant therapy Sterimar isotonic solution was prescribed 3-6 times daily over two weeks. They visited doctor office every week when they also filled out QoL standardized questionnaire. A Patient's Diary was filled out daily. Results. Symptom pattern was evaluated at three points: initial, end of 1st week, end of 2nd week. Congestion, cough and headache were significantly reduced by the end of 1st week (p<0.01) according to doctor's and patient's data. Discharge was significantly reduced by doctor's notes (p<0.01) and less by patient's observations (p<0.01 after 2nd week). QoL data have shown significant improvement after 1st week of intensive seawater solution use. There were no side effects. Conclusions. Nasal irrigation with frequent use of seawater isotonic solution is effective alleviating chronic rhinosinusitis symptoms such as nasal congestion and discharge, cough and headache. QoL has been improved already by the end of 1st week. There were limitations: number of patients and short study duration.

isotonic seawater solution, chronic rhinosinusitis

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