engleski

Inflammatory response following peripheral endovascular treatment correlates with the extent of peripheral arterial injury

Endovascular treatment (EVT), as a minimally invasive therapy, treats only a diseased vessel segment. However, dilatation with high pressure balloons and implantation of stents cause periprocedural injury of the arterial wall by endothelial denudation, as well as intimal and medial damage. These injuries are followed by inflammatory response that often ends with neointimal hyperplasia, a major culprit for long-term EVT failure. Present study has assessed the correlation between periprocedural arterial injury and inflammatory response measured by CRP and fibrinogen increase, suggesting that the extent of iatrogenic damage to the arterial wall could relate to future arterial remodeling and subsequent restenosis.

Vascular, Interventional vascular, Arteries / Aorta, Catheter arteriography, Angioplasty, Stents, Biological effects, Arteriosclerosis, Inflammation

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