Association of Chronotype and Daytime Sleepiness with Myocardial Infarction. (CROSBI ID 661832)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Škrlec, Ivana ; Milić, Jakov ; Heffer, Marija ; Steiner, Robert ; Peterlin, Borut ; Wagner, Jasenka
engleski
Association of Chronotype and Daytime Sleepiness with Myocardial Infarction.
Human physiological activities and diseases are under the control of circadian rhythm. The circadian rhythm is regulated by the suprachiasmatic nucleus (SCN) and multiple circadian clock genes. Sleep disorders are associated with vascular outcomes such as myocardial infarction (MI). Circadian rhythm is under the influence of lifestyle that can lead to MI. We conducted a cohort study of 200 patients who were hospitalized because MI and 200 healthy controls. Systematic information on the past and current medical history, plus the demographic variables was collected from each participant. Chronotype was assessed with the Morningness- Eveningness Questionnaire (MEQ) and daytime sleepiness with the Epworth Sleepiness Scale (ESS). Mean age of the study population was 64.1±12.8 years and 54.5% were males. No significant difference was found in MEQ scores among male patients versus male controls (59.3±6.4 vs. 58.3±7.6, p=0.909) and no significant difference in ESS score among two female groups (5.8±3.4 vs. 5.8±3.9, p=0.102). MEQ is associated with age in male patients (p=0.00026), but not in male controls and females. A significant association was found between ESS and dyslipidemia in patients (p=0.005) but not in the controls (p=0.228). ESS was associated with family anamneses of cardiovascular diseases in patients but not in the controls (p=0.008 vs. p=0.58). MEQ was associated with non-smoking in controls (p=0.0018). Risk factors for cardiovascular diseases, such as age, dyslipidemia, smoking, are associated with MEQ or ESS. There have been no studies to our knowledge looking specifically for differences in circadian rhythm among the MI patients and healthy controls.
cardiovascular diseases ; chronotype ; circadian rhythm ; myocardial infarction ; sleepiness
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Podaci o prilogu
MG 19
2015.
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objavljeno
978-953-57695-1-4
Podaci o matičnoj publikaciji
9th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine
Podaci o skupu
9th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine
poster
22.06.2015-26.06.2015
Bol, Hrvatska