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Pregled bibliografske jedinice broj: 938

Antioxidant-independent oxidation od low density lipoprotein


Herak, Janko Nikola; Krilov, Dubravka; Ukrainczyk, Tatjana
Antioxidant-independent oxidation od low density lipoprotein // Abstract Book of the 66th Congress of the European Atherosclerosis Society / Paoletti, R. (ur.).
Firenca, Italija: Fondazione Giovanni Lorenzini, 1966. (poster, nije recenziran, sažetak, znanstveni)


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Naslov
Antioxidant-independent oxidation od low density lipoprotein

Autori
Herak, Janko Nikola ; Krilov, Dubravka ; Ukrainczyk, Tatjana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract Book of the 66th Congress of the European Atherosclerosis Society / Paoletti, R. - Firenca, Italija : Fondazione Giovanni Lorenzini, 1966

Skup
66th Congress of the European Atherosclerosis Society

Mjesto i datum
Firenca, Italija, 13-17.07.1996

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Lipoproteins; Lipoprotein oxidation; LDL mild oxidation

Sažetak
Oxidized low density lipoprotein (LDL) has been postulated to play an important role in atherogenesis. From the in vitro studies the transition-metal ions in conjunction with preformed lipid peroxides seem to be crucial for the initiation of lipoprotein oxidation. Our experiments show that the LDL oxidation takes place also under highly unfavorable conditions for oxidation: LDL solution in the deionized water, with chelates present, in a closed system with limited access of oxygen. The dissolved oxygen is used up within hours without simultaneous loss of the lipid-soluble antioxidants, or production of the thiobarbituric-acid-reactive substances (TBARS). After depletion of oxygen, free radicals assocoated with the lipid domain are formed. These findings suggest an alternative mechanism of the LDL oxidation. LDL oxidized in this way may be termed to be mildly oxidized.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
006110

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

Profili:

Avatar Url Dubravka Krilov (autor)

Avatar Url Tatjana Ukrainczyk (autor)


Citiraj ovu publikaciju

Herak, Janko Nikola; Krilov, Dubravka; Ukrainczyk, Tatjana
Antioxidant-independent oxidation od low density lipoprotein // Abstract Book of the 66th Congress of the European Atherosclerosis Society / Paoletti, R. (ur.).
Firenca, Italija: Fondazione Giovanni Lorenzini, 1966. (poster, nije recenziran, sažetak, znanstveni)
Herak, J., Krilov, D. & Ukrainczyk, T. (1966) Antioxidant-independent oxidation od low density lipoprotein. U: Paoletti, R. (ur.)Abstract Book of the 66th Congress of the European Atherosclerosis Society.
@article{article, editor = {Paoletti, R.}, year = {1966}, pages = {134}, keywords = {Lipoproteins, Lipoprotein oxidation, LDL mild oxidation}, title = {Antioxidant-independent oxidation od low density lipoprotein}, keyword = {Lipoproteins, Lipoprotein oxidation, LDL mild oxidation}, publisher = {Fondazione Giovanni Lorenzini}, publisherplace = {Firenca, Italija} }
@article{article, editor = {Paoletti, R.}, year = {1966}, pages = {134}, keywords = {Lipoproteins, Lipoprotein oxidation, LDL mild oxidation}, title = {Antioxidant-independent oxidation od low density lipoprotein}, keyword = {Lipoproteins, Lipoprotein oxidation, LDL mild oxidation}, publisher = {Fondazione Giovanni Lorenzini}, publisherplace = {Firenca, Italija} }




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