engleski

Safe-by-design Approach for Development and Use of Antimicrobial Coatings

A state-of-the-art innovation to combat Health- Care Associated Infections (HCAIs) is the creation of self-disinfecting surfaces through the application of antimicrobial coatings (AMCs). Nanotechnology, one of the key enabling technologies, allows for significant improvements in the AMC development providing better healthcare but also enabling the design and clinical use of innovative solutions for HCAIs. However, nano-specific behavior should be taken into account during manufacturing, application and final disposal of nano-enabled AMCs at the Safe-by-Design level. This is especially relevant for exposure, absorption, distribution, accumulation, and toxic effects. The Safe-by-Design is well accepted approach to ensure safety for three different, but interrelated communities – the workplace, consumers and environment. There are following key issues: identification and characterisation of nano-based biocidal agent ; transformation of nanomaterials ; dose metrics ; fate and kinetics. It is crucial to identify difficulties related to experience and knowledge about safety assessment of AMCs. Opinions are needed to provide response, challenges, needs and recommendation for Safe-by-Design approach in addressing the application of AMCs in healthcare setting.

nanotechnology, healthcare associated infections, safety, COST Action CA15114 AMiCI

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