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Pregled bibliografske jedinice broj: 936788

Associations between apolipoprotein E genotypes and Hg concentrations in cord blood


(EU FP7 HEALS) Trdin, Anja; Falnoga, Ingrid; Snoj Tratnik, Janja; Stajnko, Anja; Mazej, Darja; Marc, Janja; Krsnik, Mladen; Osredkar, Joško; Prpić, Igor; Petrović, Oleg et al.
Associations between apolipoprotein E genotypes and Hg concentrations in cord blood // Programme and abstract book / Manno, Maurizio (ur.).
Naples, Italy: the Scientific Committee of Occupational Toxicology (SCOT) of the International Commission on Occupational Health (ICOH), in collaboration with the University of Naples Federico II, 2017. str. 83-83 (predavanje, međunarodna recenzija, sažetak, znanstveni)


Naslov
Associations between apolipoprotein E genotypes and Hg concentrations in cord blood

Autori
Trdin, Anja ; Falnoga, Ingrid ; Snoj Tratnik, Janja ; Stajnko, Anja ; Mazej, Darja ; Marc, Janja ; Krsnik, Mladen ; Osredkar, Joško ; Prpić, Igor ; Petrović, Oleg ; Špirić, Zdravko ; Horvat, Milena

Kolaboracija
EU FP7 HEALS

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Programme and abstract book / Manno, Maurizio - Naples, Italy : The Scientific Committee of Occupational Toxicology (SCOT) of the International Commission on Occupational Health (ICOH), in collaboration with the University of Naples Federico II, 2017, 83-83

Skup
10th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-10)

Mjesto i datum
Naples, Italy, 1-4 October 2017

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
apolipoprotein E, genotypes, Hg concentrations in cord blood

Sažetak
The aim of present study was to estimate the potential relations between APOE polymorphisms and concentrations of total, methyl and inorganic Hg (tHg, MeHg, iHg) in cord blood (CB) of newborns whose mothers were exposed to Hg through fish consumption. We were focused on impact of APOE polymorphism of mothers and/or their newborns, since it is not clear whose genotypes could have greater impact on placental toxicokinetics. Mothers (n=398) and newborns (n=573) from central Slovenia and coastal Croatia, participants of EU projects PHIME and CROME-LIFE+, were included in the study. We used existed data set of personal (and lifestyle) characteristics, tHg blood concentrations and archived DNA extracts from maternal leukocytes and cord tissues. CB MeHg was additionally measured by CVAFS (Tekran 2700), iHg estimated by subtraction of MeHg from tHg and DNA genotyped for APOE (rs429358 and rs7412) by TaqMan® SNP assay (Applied Biosystems). Statistics: Wilcoxon rank-sum test, multiple linear regression (STATA).

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne tehničke znanosti, Biotehnologija, Interdisciplinarne biotehničke znanosti



POVEZANOST RADA


Projekt / tema
273-0222882-2698 - Bioindikacija onečišćenja zraka u terestričkim ekosustavima (Zdravko Špirić, )

Ustanove
Medicinski fakultet, Rijeka,
OIKON d.o.o.

Profili:

Avatar Url Igor Prpić (autor)

Avatar Url Oleg Petrović (autor)

Avatar Url Zdravko Špirić (autor)

Citiraj ovu publikaciju

(EU FP7 HEALS) Trdin, Anja; Falnoga, Ingrid; Snoj Tratnik, Janja; Stajnko, Anja; Mazej, Darja; Marc, Janja; Krsnik, Mladen; Osredkar, Joško; Prpić, Igor; Petrović, Oleg et al.
Associations between apolipoprotein E genotypes and Hg concentrations in cord blood // Programme and abstract book / Manno, Maurizio (ur.).
Naples, Italy: the Scientific Committee of Occupational Toxicology (SCOT) of the International Commission on Occupational Health (ICOH), in collaboration with the University of Naples Federico II, 2017. str. 83-83 (predavanje, međunarodna recenzija, sažetak, znanstveni)
(EU FP7 HEALS) (EU FP7 HEALS) Trdin, A., Falnoga, I., Snoj Tratnik, J., Stajnko, A., Mazej, D., Marc, J., Krsnik, M., Osredkar, J., Prpić, I. & Petrović, O. (2017) Associations between apolipoprotein E genotypes and Hg concentrations in cord blood. U: Manno, M. (ur.)Programme and abstract book.
@article{article, editor = {Manno, M.}, year = {2017}, pages = {83-83}, keywords = {apolipoprotein E, genotypes, Hg concentrations in cord blood}, title = {Associations between apolipoprotein E genotypes and Hg concentrations in cord blood}, keyword = {apolipoprotein E, genotypes, Hg concentrations in cord blood}, publisher = {the Scientific Committee of Occupational Toxicology (SCOT) of the International Commission on Occupational Health (ICOH), in collaboration with the University of Naples Federico II}, publisherplace = {Naples, Italy} }