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Pregled bibliografske jedinice broj: 933383

Hyperuricemia revisited in Split, Croatia


Žužić, Furlan, Sanja; Rumboldt, Mirjana; Tomičić, Marion; Rumboldt, Zvonko
Hyperuricemia revisited in Split, Croatia // Clinical and Medical Reports, 2 (2018), 1; 1-4 doi:10.15761/CMR.1000111 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 933383 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Hyperuricemia revisited in Split, Croatia

Autori
Žužić, Furlan, Sanja ; Rumboldt, Mirjana ; Tomičić, Marion ; Rumboldt, Zvonko

Izvornik
Clinical and Medical Reports (2516-5283) 2 (2018), 1; 1-4

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
uric acid, reference values, hyperuricemia

Sažetak
Purpose: The current upper reference interval (RI) limits for serum uric acid in Croatia seemingly do not reflect the actual situation, are too low, and may instigate overdiagnosis and overtreatment with potential global implications. Methods: The study was conducted prospectively (during 2014) in 13 family medicine practices in Split, Croatia. The examinees’ sera were processed using standard uricase technology. The sample consisted of 4, 834 laboratory results ; 2, 469 pertained to apparently healthy and 2, 365 to other patients. The data were tabulated, stratified according to age and gender, and statistically analyzed. Results: The observed uric acid levels were consistently above the upper, official RI limits for Croatia (337 µmol/l for women and 403 µmol/l for men) ; over 15% of the results were definitely hyperuricemic, being higher among men and increasing in older age groups, particularly in women. Conclusions: The actual RIs for uricemia are indeed too low for the investigated south Croatian population and should be increased by some 50 µmol/l or more in most age/gender strata. Even the proposed, upgraded RIs may be of assistance in clinical judgment only, and should never be used as the exclusive criterion for clinical decisions.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Split

Profili:

Avatar Url Mirjana Rumboldt (autor)

Avatar Url Zvonko Rumboldt (autor)

Avatar Url Marion Tomičić (autor)

Citiraj ovu publikaciju

Žužić, Furlan, Sanja; Rumboldt, Mirjana; Tomičić, Marion; Rumboldt, Zvonko
Hyperuricemia revisited in Split, Croatia // Clinical and Medical Reports, 2 (2018), 1; 1-4 doi:10.15761/CMR.1000111 (međunarodna recenzija, članak, znanstveni)
Žužić, Furlan, Sanja, Rumboldt, M., Tomičić, M. & Rumboldt, Z. (2018) Hyperuricemia revisited in Split, Croatia. Clinical and Medical Reports, 2 (1), 1-4 doi:10.15761/CMR.1000111.
@article{article, year = {2018}, pages = {1-4}, DOI = {10.15761/CMR.1000111}, keywords = {uric acid, reference values, hyperuricemia}, journal = {Clinical and Medical Reports}, doi = {10.15761/CMR.1000111}, volume = {2}, number = {1}, issn = {2516-5283}, title = {Hyperuricemia revisited in Split, Croatia}, keyword = {uric acid, reference values, hyperuricemia} }
@article{article, year = {2018}, pages = {1-4}, DOI = {10.15761/CMR.1000111}, keywords = {uric acid, reference values, hyperuricemia}, journal = {Clinical and Medical Reports}, doi = {10.15761/CMR.1000111}, volume = {2}, number = {1}, issn = {2516-5283}, title = {Hyperuricemia revisited in Split, Croatia}, keyword = {uric acid, reference values, hyperuricemia} }

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