engleski

Multivariate analysis of risk factors for postoperative wound infection following oral and oropharyngeal cancer surgery

Purpose: The goal of this study is to identify risk factors for wound infections in patients with oral cancer who underwent surgical procedure. Methods: This study included 195 patients who underwent surgical treatment of oral and oropharyngeal cancer over the seven-year period. Wound infection was defined as the presence of a purulent drainage from the wound with local symptoms of infection (pain, redness, swelling). For every patient who was suspected to have a wound infection, a swab from the wound was taken and microbiological analysis was performed. The patients were divided into two groups: 1) Patients who don't have postoperative wound infection ; 2) Patients who have postoperative wound infection. Results: The overall rate of wound infection was present in 155 patients (59%). Univariate analysis indicated that the following factors were significantly related to the occurance of wound infection: gender, smoking, tumor localization, size and stage of the tumor, type of surgery, neck dissection, type of reconstruction, nasogastric sonde, gastrostomy and tracheotomy. In multivariate analysis statistically significant predictors of wound infection are: gender, tumor localization and type of reconstruction. Conslusions: Occurance of wound infection is high despite the antibiotic prophylaxis. In order to minimize the risk of wound infection and with prompt recognition of risk factors, surgeons menaging the oral tumor patients should have a better understanding of the risk factors such as gender, tumor localization and type of reconstruction.

risk factors ; wound infection ; oral cancer ; oropharyngeal cancer ; surgery ; neck dissection

nije evidentirano