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Enediyne-comprising amino aldehydes in the Passerini reaction


Glavaš, Mladena; Gredičak, Matija; Jerić, Ivanka
Enediyne-comprising amino aldehydes in the Passerini reaction // ACS Combinatorial Science, 20 (2018), 3; 151-155 doi:10.1021/acscombsci.7b00167 (međunarodna recenzija, članak, znanstveni)


Naslov
Enediyne-comprising amino aldehydes in the Passerini reaction

Autori
Glavaš, Mladena ; Gredičak, Matija ; Jerić, Ivanka

Izvornik
ACS Combinatorial Science (2156-8952) 20 (2018), 3; 151-155

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Multicomponent reactions, enediynes, Passerini reaction, receptors

Sažetak
Multicomponent reactions represent a highly efficient approach to a broad spectrum of structurally diverse compounds starting from simple and affordable compounds. A focused library of tweezers-like compounds is prepared by employing the multicomponent Passerini reaction comprising enediyne-derived amino aldehydes. The reaction proceeds under mild conditions yielding Passerini products in good to excellent yields. Post-condensation modifications of Passerini products are demonstrated through a simple deprotection/coupling approach comprising amino functionality, furnishing enediyne cores with highly decorated arms.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2014-09-3102 - Višekomponentne reakcije u sintezi peptidnih mimetika (IVANKA JERIĆ, )

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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