Enediyne-comprising amino aldehydes in the Passerini reaction (CROSBI ID 249452)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Glavaš, Mladena ; Gredičak, Matija ; Jerić, Ivanka
engleski
Enediyne-comprising amino aldehydes in the Passerini reaction
Multicomponent reactions represent a highly efficient approach to a broad spectrum of structurally diverse compounds starting from simple and affordable compounds. A focused library of tweezers-like compounds is prepared by employing the multicomponent Passerini reaction comprising enediyne-derived amino aldehydes. The reaction proceeds under mild conditions yielding Passerini products in good to excellent yields. Post-condensation modifications of Passerini products are demonstrated through a simple deprotection/coupling approach comprising amino functionality, furnishing enediyne cores with highly decorated arms.
multicomponent reactions ; enediynes ; Passerini reaction ; receptors
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Podaci o izdanju
20 (3)
2018.
151-155
objavljeno
2156-8952
2156-8944
10.1021/acscombsci.7b00167