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Pregled bibliografske jedinice broj: 927610

Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26)


Batičić Pučar, Lara; Kovač, Anja; Detel, Dijana; Buljević, Sunčica; Pernjak Pugel, Ester; Varljen, Jadranka
Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26) // Journal of tissue science & engineering, 8 (2017), 3; 213, 6 doi:10.4172/2157-7552.1000213 (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 927610 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26)

Autori
Batičić Pučar, Lara ; Kovač, Anja ; Detel, Dijana ; Buljević, Sunčica ; Pernjak Pugel, Ester ; Varljen, Jadranka

Izvornik
Journal of tissue science & engineering (2157-7552) 8 (2017), 3; 213, 6

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Dipeptidyl peptidase IV ; Molecule CD 26 ; Diabetes ; Wound healing

Sažetak
Dipeptidyl Peptidase IV or molecule CD26 (DPP IV/CD26) is a multifunctional protein, identified as a therapeutic target for type 2 diabetes, due to its ability to degrade incretins, insulin secretagogues. Delayed wound healing is a significant complication in diabetic patients that represents a major socio- economic health problem. It has been proposed that DPP IV/CD26 inhibition accelerates healing of chronic diabetic ulcers in those patients, through the induction of a histological pattern consistent with enhanced angiogenesis. Studies on mice models of diabetesdisturbed wound healing also suggested that the inhibition of DPP IV enzymatic activity may improve tissue regeneration processes. However, further research is needed to elucidate the role of DPP IV/CD26 in diabetic wound healing. The objective of this work was to discuss recent findings on the implications of DPP IV/CD26 in tissue regeneration and reparation in diabetic environment.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
062-0061245-0213 - Uloga dipeptidil-peptidaze IV (CD26/DPP IV) u kroničnim bolestima (Varljen, Jadranka, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Rijeka,
Sveučilište u Rijeci - Odjel za biotehnologiju,
Fakultet zdravstvenih studija u Rijeci

Poveznice na cjeloviti tekst rada:

doi www.omicsonline.org

Citiraj ovu publikaciju:

Batičić Pučar, Lara; Kovač, Anja; Detel, Dijana; Buljević, Sunčica; Pernjak Pugel, Ester; Varljen, Jadranka
Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26) // Journal of tissue science & engineering, 8 (2017), 3; 213, 6 doi:10.4172/2157-7552.1000213 (međunarodna recenzija, pregledni rad, znanstveni)
Batičić Pučar, L., Kovač, A., Detel, D., Buljević, S., Pernjak Pugel, E. & Varljen, J. (2017) Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26). Journal of tissue science & engineering, 8 (3), 213, 6 doi:10.4172/2157-7552.1000213.
@article{article, author = {Bati\v{c}i\'{c} Pu\v{c}ar, Lara and Kova\v{c}, Anja and Detel, Dijana and Buljevi\'{c}, Sun\v{c}ica and Pernjak Pugel, Ester and Varljen, Jadranka}, year = {2017}, pages = {6}, DOI = {10.4172/2157-7552.1000213}, chapter = {213}, keywords = {Dipeptidyl peptidase IV, Molecule CD 26, Diabetes, Wound healing}, journal = {Journal of tissue science and engineering}, doi = {10.4172/2157-7552.1000213}, volume = {8}, number = {3}, issn = {2157-7552}, title = {Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26)}, keyword = {Dipeptidyl peptidase IV, Molecule CD 26, Diabetes, Wound healing}, chapternumber = {213} }
@article{article, author = {Bati\v{c}i\'{c} Pu\v{c}ar, Lara and Kova\v{c}, Anja and Detel, Dijana and Buljevi\'{c}, Sun\v{c}ica and Pernjak Pugel, Ester and Varljen, Jadranka}, year = {2017}, pages = {6}, DOI = {10.4172/2157-7552.1000213}, chapter = {213}, keywords = {Dipeptidyl peptidase IV, Molecule CD 26, Diabetes, Wound healing}, journal = {Journal of tissue science and engineering}, doi = {10.4172/2157-7552.1000213}, volume = {8}, number = {3}, issn = {2157-7552}, title = {Wound Healing Process, Diabetes and Implications of Dipeptidyl Peptidase IV (DPP IV/CD26)}, keyword = {Dipeptidyl peptidase IV, Molecule CD 26, Diabetes, Wound healing}, chapternumber = {213} }

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