Napredna pretraga

Pregled bibliografske jedinice broj: 925408

Dietary supplementation with mannan oligosaccharide and clinoptilolite modulates innate and adaptive immune parameters of weaned pigs


(Department for Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 210-719, Olsztyn, Poland) Valpotić, Hrvoje; Žura Žaja, Ivona; Samardžija, Marko; Habrun, Boris; Ostović, Mario; Đuričić, Dražen; Maćešić, Nino; Mikulec, Željko; Kočila, Predrag; Sobiech, Przemyslaw et al.
Dietary supplementation with mannan oligosaccharide and clinoptilolite modulates innate and adaptive immune parameters of weaned pigs // Polish Journal of Veterinary Sciences, 21 (2018), 1; 83-93 doi:10.24425/119025 (međunarodna recenzija, članak, znanstveni)


Naslov
Dietary supplementation with mannan oligosaccharide and clinoptilolite modulates innate and adaptive immune parameters of weaned pigs

Autori
Valpotić, Hrvoje ; Žura Žaja, Ivona ; Samardžija, Marko ; Habrun, Boris ; Ostović, Mario ; Đuričić, Dražen ; Maćešić, Nino ; Mikulec, Željko ; Kočila, Predrag ; Sobiech, Przemyslaw ; Valpotić, Ivica ; Vince, Silvijo

Kolaboracija
Department for Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 210-719, Olsztyn, Poland

Izvornik
Polish Journal of Veterinary Sciences (1505-1773) 21 (2018), 1; 83-93

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Mannan oligosaccharide ; clinoptilolite ; innate/adaptive immunity ; weaned pigs

Sažetak
The aim of this study was to assess modulatory effects of dietary supplements mannan oligosaccharide (MOS) and clinoptilolite (CPL) as potential alternatives to antibiotic growth promoters (AGP) given to 4-week old pigs at weaning (Day 0) on their innate/adaptive immunity by determining: alterations in C- reactive protein (CRP) and haptoglobin (HpG) serum levels, efficiency of blood monocytes (MO) and neutrophilic granulocytes (GR) for in vitro phagocytosis (PHC)/microbicidity (MBC) and proportion of extrathymic double positive CD4 CD8 (CD4+CD8+) T cells throughout 35 days of the study. Neither MOS nor CPL changed the serum concentrations of CRP, whereas that of HpG was significantly increased in the CPL supplemented pigs (p<0.05) at Day 35. Activity of PHA of GR was significantly increased by both dietary supplements (p<0.05) from Day 7 to Day 35. Also, the GR from pigs fed with both supplements had significantly increased MBC at Day 7 (p<0.05), but at Day 35 such an increase was observed only for CPL. The in vitro PHC/MBC of MO did not change in either group of supplemented pigs. The pigs supplemented with MOS had a significantly higher proportion of CD4+CD8+ T lymphocytes at Day 28 (p<0.05). Although both supplements showed a promising ability to stimulate rather innate than adaptive cellular immunity, it does not appear that any solely applied natural substance such as MOS or CPL in the current study could be a competitive alternative to conventional AGP for improving health and promoting growth in weaned pigs.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • BIOSIS Previews (Biological Abstracts)
  • CAB Abstracts


Citati