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Pregled bibliografske jedinice broj: 921216

Broad-spectrum resistance of Pseudomonas aeruginosa from shellfish: infrequent acquisition of novel resistance mechanisms


Maravić, Ana; Šamanić, Ivica; Šprung, Matilda; Fredotović, Željana; Ilić, Nada; Dragičević, Josipa; Puizina, Jasna
Broad-spectrum resistance of Pseudomonas aeruginosa from shellfish: infrequent acquisition of novel resistance mechanisms // Environmental monitoring and assessment, 190 (2018), 190, 81 doi:10.1007/s10661-018-6471-3 (međunarodna recenzija, članak, znanstveni)


Naslov
Broad-spectrum resistance of Pseudomonas aeruginosa from shellfish: infrequent acquisition of novel resistance mechanisms

Autori
Maravić, Ana ; Šamanić, Ivica ; Šprung, Matilda ; Fredotović, Željana ; Ilić, Nada ; Dragičević, Josipa ; Puizina, Jasna

Izvornik
Environmental monitoring and assessment (0167-6369) 190 (2018); 190, 81

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Efflux study ; ESBL ; mytilus galloprovincialis ; marine environment ; pseudomonas aeruginosa

Sažetak
Pseudomonas aeruginosa is one the most common multidrug-resistant pathogens worldwide. It has been previously detected in marine shellfish, but its antibiotic resistance in such environment has not been explored. By combining PCR detection of acquired genes, and resistance-nodulation-cell division (RND) efflux studying, we investigated the multifactorial resistance traits of 108 P. aeruginosa isolates recovered from wild-growing Mediterranean mussels (Mytilus galloprovincialis) in Croatia. Eleven different resistance profiles were found, with the main mechanism being the overexpression of intrinsic efflux pump(s), particularly MexAB-OprM. Several acquired resistance determinants were detected, including the β-lactamase gene blaTEM-116, sulfamethoxazole resistance gene sul1, and the class 1 integron gene cassette carrying the streptomycin resistance gene aadA7. This study evidenced the multiple resistance in P. aeruginosa in shellfish from human-impacted marine environment, pointing to the underestimated role of the marine habitat for maintenance of multiresistant P. aeruginosa and, consequently, the potential risk for human and environmental health.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekt / tema
177-1191196-0829 - Mehanizmi očuvanja stabilnosti genoma u viših biljaka (Jasna Puizina, )

Ustanove
Prirodoslovno-matematički fakultet, Split

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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