engleski

The recent state of a hundred years old classic hypothesis of the cerebrospinal fluid physiology

The knowledge of cerebrospinal fluid (CSF) physiology is mainly presented in hypotheses. Today there are two relevant hypotheses on CSF physiology ; the classic one, known as the third circulation (1, 2), and the new one (3-5). The classic hypothesis is still predominantly present in medical and scientific literature, and new experimental based knowledge is unfortunately still not sufficiently involved in discussions about CSF physiology. However, we hope that in time, the framework of thinking associated with education within the classic hypothesis is becoming more and more tolerable and that the hypothesis, which corresponds to experimental and clinical results, and physiological relationships in the central nervous system will take an objective place in CSF physiology.

Cerebrospinal fluid, Classical hypothesis, Bulat-Klarica-Orešković hypothesis

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