engleski

Premature twins with acute renal injury – it is not always what it seems to be: case study

Acute kidney injury (AKI) is common in critically ill premature infants. They are more susceptible to renal injury than older infants and children because of the functional and developmental immaturity of neonatal kidney. There is no unified definition for neonatal AKI. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well. The serum creatinine (SCr) concentration at birth is similar to motherˈs value. We present a case of prematurely born twins who were admitted to intensive care unit because of acute renal injury. The laboratory examination results showed equally elevated levels of blood urea nitrogen (BUN) and SCr in both twins and metabolic alcalosis. High values of BUN and SCr were are a result of the mother's unrecognized renal disease. On the seventh postnatal day, SCr and BUN were within normal ranges. In all cases of high SCr levels in neonates in the first 48 hours it is mandatory to check the motherˈs renal function.

acute kidney injury ; infant ; premature ; uremia

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