Telomeres, Nutrition and Longevity – Can we really navigate our aging (CROSBI ID 246205)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Škrobot Vidaček, Nikolina ; Nanić, Lucia ; Ravlić, Sanda ; Sopta, Mary ; Gerić, Marko ; Gajski, Goran ; Garaj-Vrhovac, Vera ; Rubelj, Ivica
engleski
Telomeres, Nutrition and Longevity – Can we really navigate our aging
Telomeres are dynamic chromosome-end structures that serve as guardians of genome stability. They are known to be one of the major determinants of aging and longevity in higher mammals. Studies have demonstrated a direct correlation between telomere length and life expectancy, stress, DNA damage, and onset of aging-related diseases. This review discusses the most important factors that influence our telomeres. Various genetic and environmental factors such as diet, physical activity, obesity, and stress are known to influence health and longevity as well as telomere dynamics. Individuals currently have the opportunity to modulate the dynamics of their aging and health span, monitor these processes, and even make future projections by following their telomere dynamics. As telomeres react to positive as well as negative health factors, we should be able to directly influence our telomere metabolism, slow their deterioration, and diminish our aging and perhaps extend our life and health span.
Telomeres, Human aging, Longevity, Dietary restriction
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Podaci o izdanju
73 (1)
2017.
39-47
objavljeno
1079-5006
1758-535X
10.1093/gerona/glx082
Povezanost rada
Biologija