Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi

Differences in neurohumoral and hemodynamic response to prolonged head-up tilt between patients with high and normal standing norepinephrine forms of postural orthostatic tachycardia syndrome (CROSBI ID 246166)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Crnošija, Luka ; Krbot Skorić, Magdalena ; Lovrić, Mila ; Junaković, Anamari ; Miletić, Vladimir ; Šprljan Alfirev, Rujana ; Pavelić, Antun ; Adamec, Ivan ; Habek, Mario Differences in neurohumoral and hemodynamic response to prolonged head-up tilt between patients with high and normal standing norepinephrine forms of postural orthostatic tachycardia syndrome // Autonomic neuroscience: basic & clinical, 205 (2017), 110-114. doi: 10.1016/j.autneu.2017.05.007

Podaci o odgovornosti

Crnošija, Luka ; Krbot Skorić, Magdalena ; Lovrić, Mila ; Junaković, Anamari ; Miletić, Vladimir ; Šprljan Alfirev, Rujana ; Pavelić, Antun ; Adamec, Ivan ; Habek, Mario

engleski

Differences in neurohumoral and hemodynamic response to prolonged head-up tilt between patients with high and normal standing norepinephrine forms of postural orthostatic tachycardia syndrome

Objective was to investigate the optimal timing for blood sample collection of catecholamines and the possible correlations between neurohumoral and hemodynamic responses to prolonged head-up tilt (HUT) in postural orthostatic tachycardia syndrome (POTS). Nineteen patients underwent a 30-minute, 70° HUT test. Blood samples (norepinephrine (NE), epinephrine and dopamine) were taken in the 10th minute of supine, and 10th, 20th and 30th minutes of HUT. There were no significant differences in the proportion of high and normal standing NE patients in the different time points. Mean NE (nmol/L) values in 10th, 20th and 30th minute of HUT were 4.37, 4.87, and 4.35 in the high standing NE, and 2.49, 2.59 and 2.88 in the normal standing NE group. High standing NE patients had higher blood pressure (BP) during the first 6min of HUT (2nd minute after the HUT systolic BP (sBP): 118.29±15.65 vs. 95.70±13.43, p=0.004 ; diastolic BP (dBP): 78.71±6.68 vs. 65.10±9.04, p=0.003), while normal standing NE patients exhibited a drop in BP compared to resting values during the same time period. The normal standing NE group exhibited a progressive increase in norepinephrine values during the HUT. One blood sample taken at the 10th minute of HUT correctly identifies high and normal standing NE POTS patients, but a small number of patients (1 out of 19, 5.2%) can be misidentified. High and normal standing NE POTS patients display distinctly different neurohumoral and hemodynamic responses to HUT.

Dopamine ; Epinephrine ; High standing NE ; Norepinephrine ; Postural orthostatic tachycardia syndrome

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o izdanju

205

2017.

110-114

objavljeno

1566-0702

1872-7484

10.1016/j.autneu.2017.05.007

Povezanost rada

Kliničke medicinske znanosti, Interdisciplinarne biotehničke znanosti

Poveznice
Indeksiranost