engleski

Ra – Rapid de novo genome assembler

Ra is a novel de novo genome assembler based on the Overlap-Layout-Consensus paradigm tailored for reads produced by third generation sequencing platforms. It integrates previously developed Minimap overlap (Li, 2016), Racon consensus (Vaser et al, 2017) tools and a newly developed layout module Rala into one package. Omitting time consuming error correction in the preprocessing step enables fast genome assembly while keeping high accuracy levels. The achieved results on several read datasets generated by the Pacific Biosciences sequencing platforms are comparable with those of similar de novo assemblers Hinge (Kamath et al, 2017) and Miniasm+Racon in contiguity, accuracy and running time.

de novo assembly, long reads

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