Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 914754

Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children


Bašković, Marko; Župančić, Božidar; Dominković, Ana; Čizmić, Ante; Ježek, Davor
Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children // International Journal of Pediatrics, 6 (2018), 1; 6851-6859 doi:10.22038/ijp.2017.26748.2304 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 914754 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children

Autori
Bašković, Marko ; Župančić, Božidar ; Dominković, Ana ; Čizmić, Ante ; Ježek, Davor

Izvornik
International Journal of Pediatrics (2345-5047) 6 (2018), 1; 6851-6859

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Appendicitis ; Children ; Leukocytes ; Segmented neutrophils

Sažetak
Background: Appendicitis is the most common indication for an emergency operation in children's age. Although none of the laboratory values has not high sensitivity and specificity for the diagnosis of appendicitis, leukocyte count and the percentage of segmented neutrophils are most commonly used. The aim of this study was to determine whether there is a statistically significant correlation between leukocyte count and the percentage of segmented neutrophils compared to the pathohistological finding of appendix in children. Materials and Methods: We retrospectively analyzed the data in the period from 1 January 2016 to 31 December 2016. The analysis was made on 211 patients (from the Children's Hospital Zagreb, Croatia). Spearman's correlation coefficient (rs) was calculated. We determined the specificity and sensitivity of leukocyte count and the percentage of segmented neutrophils used in the calculation of Alvorado and Pediatric Appendicitis score. Results: The results of the research have shown that the correlation between leukocyte count and the pathohistological findings is weak (rs = 0.29, p = 3.61*10-8) ; while there is no correlation between the percentage of segmented neutrophils and pathohistological findings (rs = 0.18, p = 7.08 *10-5). The sensitivity of leukocyte count is 93% and the specificity is 30%, while the sensitivity to the percentage of segmented neutrophils is 71% and the specificity is 50%. The Receiver Operating Characteristic (ROC) curve analysis for leukocytes shows area under the curve of 0.648, while for segmented neutrophils of 0.574. Conclusion: Given the correlation results obtained, the clinical experience of physicians will still have one of the leading roles in diagnosing acute appendicitis in children.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Zagreb,
Klinika za dječje bolesti

Profili:

Avatar Url Davor Ježek (autor)

Avatar Url Ante Čizmić (autor)

Avatar Url Božidar Župančić (autor)

Citiraj ovu publikaciju

Bašković, Marko; Župančić, Božidar; Dominković, Ana; Čizmić, Ante; Ježek, Davor
Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children // International Journal of Pediatrics, 6 (2018), 1; 6851-6859 doi:10.22038/ijp.2017.26748.2304 (međunarodna recenzija, članak, znanstveni)
Bašković, M., Župančić, B., Dominković, A., Čizmić, A. & Ježek, D. (2018) Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children. International Journal of Pediatrics, 6 (1), 6851-6859 doi:10.22038/ijp.2017.26748.2304.
@article{article, year = {2018}, pages = {6851-6859}, DOI = {10.22038/ijp.2017.26748.2304}, keywords = {Appendicitis, Children, Leukocytes, Segmented neutrophils}, journal = {International Journal of Pediatrics}, doi = {10.22038/ijp.2017.26748.2304}, volume = {6}, number = {1}, issn = {2345-5047}, title = {Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children}, keyword = {Appendicitis, Children, Leukocytes, Segmented neutrophils} }
@article{article, year = {2018}, pages = {6851-6859}, DOI = {10.22038/ijp.2017.26748.2304}, keywords = {Appendicitis, Children, Leukocytes, Segmented neutrophils}, journal = {International Journal of Pediatrics}, doi = {10.22038/ijp.2017.26748.2304}, volume = {6}, number = {1}, issn = {2345-5047}, title = {Correlation of Leukocyte Count and Percentage of Segmented Neutrophils with Pathohistological Findings of Appendix in Children}, keyword = {Appendicitis, Children, Leukocytes, Segmented neutrophils} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font