Meso- and racemic- DMSA as antidotes in heavy metal poisoning (CROSBI ID 485188)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Blanuša, Maja ; Piasek, Martina ; Kostial, Krista ; Jones, Mark M. ; Singh, Pramod K.
engleski
Meso- and racemic- DMSA as antidotes in heavy metal poisoning
The results of our investigations presented and reviewed in this paper have been obtained in experimental animal models in vivo and published earlier. Two chelating agents were compared for their mobilising potency of reducing lead, cadmium and mercury body retention. The results show that the racemic isoform of DMSA is more efficient in reducing the body burden and target organ retention of toxic metals than meso-DMSA. The efficiency of metal body burden reduction with rac-DMSA was ordered: mercury>lead>cadmium. These studies will be continued to assess whether rac-DMSA could be applied clinically.
lead; cadmium; mercury; meso- and racemic-1; 3-dimercaptosuccinic acid
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Podaci o prilogu
91-95-x.
2002.
objavljeno
Podaci o matičnoj publikaciji
Proceedings of the Chemical and Biological Medical Treatment Symposium - CBMTS - Industry II
Bokan, Slavko ; Orehovec, Zvonko
Zagreb : Aberdeen (MD):
Podaci o skupu
Nepoznat skup
poster
29.02.1904-29.02.2096