engleski

Genetics of Sleep

Molecular and genetic approaches in several species have provided new insights into the mechanisms of rest-activity and sleep-wake regulation. Many of these discoveries are believed to support hypotheses about sleep functions, which nevertheless remain elusive. In this review we discuss the specific contribution of both mammalian and invertebrate models to our understanding of the molecular basis of sleep.

recombinant inbred mice ; long-term-memory ; Drosophila-hyperkinetic mutants ; quantitative trait loci ; eye-movement sleep ; slow-wave sleep ; knock-out mice ; rem-sleep ; mushroom bodies ; circadian pacemaker

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