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Predisposing factors for metabolic syndrome in pregnancy and newborns` body size: preliminary report from the CRoatian Islands` Birth Cohort Study (CROSBI ID 653931)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija

Havaš Auguštin, Dubravka ; Zajc Petranović, Matea ; Šarac, Jelena ; Carić, Tonko ; Perinić Lewis, Ana ; Novokmet, Natalija ; Pribačić Ambrožić, Vanda ; Sindik, Joško ; Čoklo, Miran ; Karelović, Deni et al. Predisposing factors for metabolic syndrome in pregnancy and newborns` body size: preliminary report from the CRoatian Islands` Birth Cohort Study // Journal of Developmental Origins of Health and Disease / Jaddoe, W.V. (ur.). 2017. str. S75-S76 doi: 10.1017/S2040174417000848

Podaci o odgovornosti

Havaš Auguštin, Dubravka ; Zajc Petranović, Matea ; Šarac, Jelena ; Carić, Tonko ; Perinić Lewis, Ana ; Novokmet, Natalija ; Pribačić Ambrožić, Vanda ; Sindik, Joško ; Čoklo, Miran ; Karelović, Deni ; Škrabić, Veselin ; Žižić, Ana ; Stanišić, Lada ; Orehovec, Biserka ; Romić, Željko ; Janković, Stipan ; Cameron, Noel ; Demerath, Ellen ; Schell Lawrence ; Missoni, Saša

engleski

Predisposing factors for metabolic syndrome in pregnancy and newborns` body size: preliminary report from the CRoatian Islands` Birth Cohort Study

The prevalence of Metabolic Syndrome (MetS) on Eastern Adriatic islands is higher than in neighboring mainland area. The CRoatian Islands` Birth Cohort Study (CRIBS) is an ongoing 3-year-project with an aim to assess the prevalence of known risk factors for MetS. The CRIBS sample consists of pregnant women from Dalmatian islands Brač and Hvar and nearby coastal town Split and its surroundings, who had no history of chronic diseases (particularly MetS), who conceived naturally and had singleton pregnancies, and their newborns. We tested the association of possible predisposing factors for MetS (age, smoking, prepregnancy BMI, fasting blood biochemical parameters) and newborns` anthropometric measures. In this preliminary sample (n=131, age range 19.8-41.7 yrs, mean 30.6±4.6 yrs), 28.3% of women reported smoking in pregnancy and 22.2% reported being exposed to passive smoking. 17.9% of all the women were overweight and 4.7% were obese. In comparison to underweight women (<18.5 kg/m2), obese pregnant women gave birth to heavier (p<0.05) and taller babies (p<0.01). Newborns of primi- and multiparous mothers were significantly taller (p<0.05) and had bigger head circumference (p<0.001) than newborns of nulliparous mothers. Women with higher mean triglyceride levels more often had large for gestational age than normal for gestational age children (p<0.01). Smokers, in comparison to non-smokers, had significantly higher triglycerides (p<0.05) and lower HDL cholesterol (p<0.01). All the predisposing factors for MetS were compared according to the island and mainland place of residence: newborns` size at birth (weight, length and head circumference, z-standardized according to WHO) did not differ between the two groups. The only difference was detected in women ; islanders had higher glucose (p<0.05), while women from the mainland had higher homocysteine and lipoprotein(a) (both p<0.05). Despite none of the investigated women was diagnosed with MetS, some of its components have a considerable prevalence in the investigated CRIBS population.

birth cohort, CRIBS, metabolic syndrome, pregnancy, newborns, Croatia

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nije evidentirano

nije evidentirano

Podaci o prilogu

S75-S76.

2017.

nije evidentirano

objavljeno

10.1017/S2040174417000848

Podaci o matičnoj publikaciji

Journal of Developmental Origins of Health and Disease

Jaddoe, W.V.

Cambridge University Press

2040-1744

2040-1752

Podaci o skupu

10th World Congress on Developmental Origins of Heatht and Disease

poster

15.10.2017-18.10.2017

Rotterdam, Nizozemska

Povezanost rada

Biologija, Kliničke medicinske znanosti, Temeljne medicinske znanosti

Poveznice
Indeksiranost