Predisposing factors for metabolic syndrome in pregnancy and newborns` body size: preliminary report from the CRoatian Islands` Birth Cohort Study (CROSBI ID 653931)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Havaš Auguštin, Dubravka ; Zajc Petranović, Matea ; Šarac, Jelena ; Carić, Tonko ; Perinić Lewis, Ana ; Novokmet, Natalija ; Pribačić Ambrožić, Vanda ; Sindik, Joško ; Čoklo, Miran ; Karelović, Deni ; Škrabić, Veselin ; Žižić, Ana ; Stanišić, Lada ; Orehovec, Biserka ; Romić, Željko ; Janković, Stipan ; Cameron, Noel ; Demerath, Ellen ; Schell Lawrence ; Missoni, Saša
engleski
Predisposing factors for metabolic syndrome in pregnancy and newborns` body size: preliminary report from the CRoatian Islands` Birth Cohort Study
The prevalence of Metabolic Syndrome (MetS) on Eastern Adriatic islands is higher than in neighboring mainland area. The CRoatian Islands` Birth Cohort Study (CRIBS) is an ongoing 3-year-project with an aim to assess the prevalence of known risk factors for MetS. The CRIBS sample consists of pregnant women from Dalmatian islands Brač and Hvar and nearby coastal town Split and its surroundings, who had no history of chronic diseases (particularly MetS), who conceived naturally and had singleton pregnancies, and their newborns. We tested the association of possible predisposing factors for MetS (age, smoking, prepregnancy BMI, fasting blood biochemical parameters) and newborns` anthropometric measures. In this preliminary sample (n=131, age range 19.8-41.7 yrs, mean 30.6±4.6 yrs), 28.3% of women reported smoking in pregnancy and 22.2% reported being exposed to passive smoking. 17.9% of all the women were overweight and 4.7% were obese. In comparison to underweight women (<18.5 kg/m2), obese pregnant women gave birth to heavier (p<0.05) and taller babies (p<0.01). Newborns of primi- and multiparous mothers were significantly taller (p<0.05) and had bigger head circumference (p<0.001) than newborns of nulliparous mothers. Women with higher mean triglyceride levels more often had large for gestational age than normal for gestational age children (p<0.01). Smokers, in comparison to non-smokers, had significantly higher triglycerides (p<0.05) and lower HDL cholesterol (p<0.01). All the predisposing factors for MetS were compared according to the island and mainland place of residence: newborns` size at birth (weight, length and head circumference, z-standardized according to WHO) did not differ between the two groups. The only difference was detected in women ; islanders had higher glucose (p<0.05), while women from the mainland had higher homocysteine and lipoprotein(a) (both p<0.05). Despite none of the investigated women was diagnosed with MetS, some of its components have a considerable prevalence in the investigated CRIBS population.
birth cohort, CRIBS, metabolic syndrome, pregnancy, newborns, Croatia
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nije evidentirano
Podaci o prilogu
S75-S76.
2017.
nije evidentirano
objavljeno
10.1017/S2040174417000848
Podaci o matičnoj publikaciji
Journal of Developmental Origins of Health and Disease
Jaddoe, W.V.
Cambridge University Press
2040-1744
2040-1752
Podaci o skupu
10th World Congress on Developmental Origins of Heatht and Disease
poster
15.10.2017-18.10.2017
Rotterdam, Nizozemska
Povezanost rada
Biologija, Kliničke medicinske znanosti, Temeljne medicinske znanosti