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Pregled bibliografske jedinice broj: 894962

Rutin as neuroprotective agent: from bench to bedside


Budzynska, Barbara; Faggio, Caterina; Kruk- Slomka, Marta; Šamec, Dunja; Nabavi, Seyed Fazel; Sureda, Antoni; Devi, Kasi Pandima; Nabavi, Seyed Mohammad
Rutin as neuroprotective agent: from bench to bedside // Current medicinal chemistry, 26 (2019), 1-11 doi:10.2174/0929867324666171003114154 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Rutin as neuroprotective agent: from bench to bedside

Autori
Budzynska, Barbara ; Faggio, Caterina ; Kruk- Slomka, Marta ; Šamec, Dunja ; Nabavi, Seyed Fazel ; Sureda, Antoni ; Devi, Kasi Pandima ; Nabavi, Seyed Mohammad

Izvornik
Current medicinal chemistry (0929-8673) 26 (2019); 1-11

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Alzheimer's disease ; antioxidant ; flavonoid ; neurodegenerative diseases ; polyphenols ; rutin

Sažetak
Lavonoids are major dietary constituents of plant-based food that occur ubiquitously in plant kingdom where they are usually present in substantial amounts. Rutin is a flavonol-type polyphenol and consists of the flavonol quercetin and the disaccharide rutinose. Rutin has been reported to exert divers biological effects such as antitumor and antimicrobial mainly associated to its antioxidant and anti- inflammatory activities. Mental, neurological, and behavioural disorders are an important and growing cause of morbidity. Most of these disorders combine a high prevalence, early onset, progressive clinical course, and impairment of critical brain functions making them a major contributor to the global disease burden. In the present work the biological in vitro and in vivo effects and the potential therapeutic applications of rutin in neurodegenerative processes is reviewed, as well as their bioavailability and pharmacokinetics, which is essential for a better understanding of its biological effectiveness. Moreover, the present review also provides an overview of the molecular mechanisms through which rutin are proposed to exert its neuroprotective effects.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Dunja Šamec (autor)

Poveznice na cjeloviti tekst rada:

doi www.eurekaselect.com

Citiraj ovu publikaciju:

Budzynska, Barbara; Faggio, Caterina; Kruk- Slomka, Marta; Šamec, Dunja; Nabavi, Seyed Fazel; Sureda, Antoni; Devi, Kasi Pandima; Nabavi, Seyed Mohammad
Rutin as neuroprotective agent: from bench to bedside // Current medicinal chemistry, 26 (2019), 1-11 doi:10.2174/0929867324666171003114154 (međunarodna recenzija, pregledni rad, znanstveni)
Budzynska, B., Faggio, C., Kruk- Slomka, M., Šamec, D., Nabavi, S., Sureda, A., Devi, K. & Nabavi, S. (2019) Rutin as neuroprotective agent: from bench to bedside. Current medicinal chemistry, 26, 1-11 doi:10.2174/0929867324666171003114154.
@article{article, author = {Budzynska, Barbara and Faggio, Caterina and Kruk- Slomka, Marta and \v{S}amec, Dunja and Nabavi, Seyed Fazel and Sureda, Antoni and Devi, Kasi Pandima and Nabavi, Seyed Mohammad}, year = {2019}, pages = {1-11}, DOI = {10.2174/0929867324666171003114154}, keywords = {Alzheimer's disease, antioxidant, flavonoid, neurodegenerative diseases, polyphenols, rutin}, journal = {Current medicinal chemistry}, doi = {10.2174/0929867324666171003114154}, volume = {26}, issn = {0929-8673}, title = {Rutin as neuroprotective agent: from bench to bedside}, keyword = {Alzheimer's disease, antioxidant, flavonoid, neurodegenerative diseases, polyphenols, rutin} }
@article{article, author = {Budzynska, Barbara and Faggio, Caterina and Kruk- Slomka, Marta and \v{S}amec, Dunja and Nabavi, Seyed Fazel and Sureda, Antoni and Devi, Kasi Pandima and Nabavi, Seyed Mohammad}, year = {2019}, pages = {1-11}, DOI = {10.2174/0929867324666171003114154}, keywords = {Alzheimer's disease, antioxidant, flavonoid, neurodegenerative diseases, polyphenols, rutin}, journal = {Current medicinal chemistry}, doi = {10.2174/0929867324666171003114154}, volume = {26}, issn = {0929-8673}, title = {Rutin as neuroprotective agent: from bench to bedside}, keyword = {Alzheimer's disease, antioxidant, flavonoid, neurodegenerative diseases, polyphenols, rutin} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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