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Pregled bibliografske jedinice broj: 89335

Prognostic factors of gastrointestinal stromal tumors


Kovač, Dražen; Petrovečki, Mladen; Jašić, Mladen; Dobi-Babić, Renata; Ivaniš, Nikola; Rubinić, Milivoj; Križanac, Šimun; Jonjić, Nives; Rizzardi, Clara; Melato, Mauro
Prognostic factors of gastrointestinal stromal tumors // Anticancer Research, 22 (2002), 369; 1913-1918 (međunarodna recenzija, članak, znanstveni)


Naslov
Prognostic factors of gastrointestinal stromal tumors

Autori
Kovač, Dražen ; Petrovečki, Mladen ; Jašić, Mladen ; Dobi-Babić, Renata ; Ivaniš, Nikola ; Rubinić, Milivoj ; Križanac, Šimun ; Jonjić, Nives ; Rizzardi, Clara ; Melato, Mauro

Izvornik
Anticancer Research (0250-7005) 22 (2002), 369; 1913-1918

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Gist; Intestine; Stomach; Flow-cytometry; Prognosis
(Gist; intestine; stomach; flow-cytometry; prognosis)

Sažetak
Gastrointestinal stromal tumors (GIST) are rare neoplasms of unknown etiology and pathogenesis. Their clinical behavior is very unpredictable and a reliable prognostic factor is lacking. The aim of this study was to analyze some prognostic factors and estimate which one is the most reliable. Thirty-eight biopsy specimens of GIST were immunolabeled for PCNA, CD34, vimetin, NSE and actin. The greatest diameter, histological grading, mitotic count, DNA-index and S-phase were estimated for each case. All patients were followed-up for at least 24 months or to death. The data were analysed by univariate and multivariate statistical analysis using a computer program. The results showed that greatest diameter, tumor grade, mitotic count and PCNA-index are prognostic factors in univariate analysis. In multivariate analysis only the greatest diameter is a useful prognostic factor for planning further therapy.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita



POVEZANOST RADA


Ustanove
Medicinski fakultet, Rijeka,
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE