Urolithiasis and Osteoporosis: Clinical Relevance and Therapeutic Implications (CROSBI ID 650596)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Bilić-Čurčić, Ines ; Milas-Ahić, Jasminka ; Smolić, Martina ; Smolić, Robert ; Mihaljević, Ivan ; Tucak Zorić, Sandra ; Omanović, Tea ; Kuna, Lucija ; Jakab, Jelena
engleski
Urolithiasis and Osteoporosis: Clinical Relevance and Therapeutic Implications
Several clinical and epidemiological studies revealed increased bone turnover and lower bone mass in patients with urolithiasis. Bone mass loss is particularly evident in idiopathic calcium stone formers. However, pathogenetic mechanisms and factors implicated in bone loss in these patients are still unknown. Dietary calcium restriction, increased intake of salt and animal proteins, vitamin D receptor polymorphisms are likely risk factors, while role of inflammatory cytokines, osteopontin and prostaglandin mediated bone resorption is yet to be determined. Regarding treatment and prevention, it has been proven that calcium supplements and high calcium diet with the addition of potassium alkali have an important role in prevention and treatment of both, urolithiasis and osteoporosis. Thiazide diuretics reduce hypercalciuria in renal tubules, and in addition promote osteoblast differentiation. Finally, bisphosphonates, a commonly used drugs in treatement of osteoporosis, show the potential to inhibit calcium stone formation, whereas a possible protective effect of antioxidants in bone loss and renal injurie needs to be investigated further.
osteporosis ; urolithiasis ; bone loss ; prevention ; treatment
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nije evidentirano
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Podaci o prilogu
30-30.
2017.
objavljeno
Podaci o matičnoj publikaciji
Knjiga sažetaka: 12. osječki urološki dani, 5. osječki nefrološki dani, 4. sekcija medicinskih sestara i tehničara urologije i nefrologije
Osijek:
Podaci o skupu
12. osječki urološki dani/ 5. osječki nefrološki dani
poster
11.05.2017-13.05.2017
Osijek, Hrvatska