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Pregled bibliografske jedinice broj: 885625

Chemical toxicity and radioactivity of depleted uranium : The evidence from in vivo and in vitro studies


Asić, Adna; Kurtović-Kozarić, Amina.; Bešić, Larisa; Mehinović, Leila; Hasić, Aazra; Kozarić, Mirza; Hukić, Mirsada; Marjanović, Damir
Chemical toxicity and radioactivity of depleted uranium : The evidence from in vivo and in vitro studies // Environmental research, 156 (2017), 665-673 doi:10.1016/j.envres.2017.04.032 (međunarodna recenzija, pregledni rad, znanstveni)


Naslov
Chemical toxicity and radioactivity of depleted uranium : The evidence from in vivo and in vitro studies

Autori
Asić, Adna ; Kurtović-Kozarić, Amina. ; Bešić, Larisa ; Mehinović, Leila ; Hasić, Aazra ; Kozarić, Mirza ; Hukić, Mirsada ; Marjanović, Damir

Izvornik
Environmental research (0013-9351) 156 (2017); 665-673

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Chemical toxicity ; Depleted uranium ; Exposure ; Radioactivity ; in vivo and in vitro studies

Sažetak
The main aim of this review is to summarize and discuss the current state of knowledge on chemical toxicity and radioactivity of depleted uranium (DU) and their effect on living systems and cell lines. This was done by presenting a summary of previous investigations conducted on different mammalian body systems and cell cultures in terms of potential changes caused by either chemical toxicity or radioactivity of DU. In addition, the authors aimed to point out the limitations of those studies and possible future directions. The majority of both in vitro and in vivo studies performed using animal models regarding possible effects caused by acute or chronic DU exposure has been reviewed. Furthermore, exposure time and dose, DU particle solubility, and uranium isotopes as factors affecting the extent of DU effects have been discussed. Special attention has been dedicated to chromosomal aberrations, DNA damage and DNA breaks, as well as micronuclei formation and epigenetic changes, as DU has recently been considered a possible causative factor of all these processes. Therefore, this approach might represent a novel area of study of DU-related irradiation effects on health. Since different studies offer contradictory results, the main aim of this review is to summarize and briefly discuss previously obtained results in order to identify the current opinion on DU toxicity and radioactivity effects in relation to exposure type and duration, as well as DU properties.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove
Institut za antropologiju

Autor s matičnim brojem:
Damir Marjanović, (279190)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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