engleski

Sensitive Electrochemical Determination of Folic Acid Using <i>ex–situ</i> Prepared Bismuth Film Electrodes

The electrochemical behavior of folic acid (FA), at the electrochemically prepared ex situ bismuth film (BiF) on glassy carbon electrode, clearly indicates electrocatalytic nature of the prepared film toward FA reduction (at –0.55 V). Scanning electron microscopy is used for morphological characterization of the prepared BiF. Accordingly, we establishing an electrochemical procedure based on square wave cathodic stripping voltammetry, preceded by accumulation of FA on the BiF electrode (BiFE). This analytical method is optimized and its analytical performance is presented. This electrode displays a two linear response range: 0.1 to 1.0 μmol L–1 and 1.0 – 10.0 μmol L–1 with sensitivity of 20.10 μA μmol–1 L and 2.28 μA μmol–1 L, respectively. Developed method was validated in compliance with spectrophotometric method. Excellent recovery and standard deviation obtained with BiFE revealed great analytical potential of the proposed method which was applied for the determination of FA in pharmaceuticals formulation.

bismuth film ; folic acid ; voltammetry ; electroanalytical

DOI: 10.5562/cca3162 ; Published online: August 8, 2017 ; CCA Vol.90 No.2 online first ; Early View - Online Version of Record published before inclusion in an issue ; FAQ-ovi 7, 8 i 2 ; 2017- 09-08, admin Glavni autor: Nives Vladislavić