engleski

Dynamics of Copper(II) Complexes with Chiral Amino Acids Studied by EPR

The basic macromolecules of life are DNA, RNA, proteins and polysaccharides. Some components can exist in two enantiomeric forms, the D and L forms. In living organisms, only one enantiomer is selected: D-sugars and L-amino acids. However, there are some exceptions and some D- amino acids occur naturally. Furthermore, copper(II) complexes with amino acids serve as models for metalloproteins and transport types of copper which are involved in a wide range of important biological processes. Therefore, the dynamical behavior of copper(II) bis-complexes with selected chiral amino acid (nonpolar, polar and electrically charged) was studied by electron paramagnetic resonance (EPR) spectroscopy as the EPR is spectroscopic tool with a long history of the study of copper(II) complexes. The cis and trans isomers were confirmed by simulation of EPR spectra for both L - and D - enantiomers. The influence of chirality on rotational motion of Cu(II)-amino acids complexes was examined.

EPR ; copper(II) complexes with amino acids ; rotation

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