engleski

NITRIC OXIDE: A ROLE IN LEBER’S HEREDITARY OPTIC NEUROPATHY

Peripheral blood mononuclear cells (PBMCs), derived from a female LHON patient with bilateral reduced vision and carrying the pathogenic mutation 11778/ND4 were observed. Viability assays with the tetrazolium dye MTT showed that lymphoblasts from the patient are more sensitive to prolonged NO exposure, leading to cell death.

Leber’s hereditary optic neuropathy ; nitric oxide

nije evidentirano