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Pregled bibliografske jedinice broj: 879283

Synthesis and complexation properties of calix[4]arene glycoconjugates


Cindro, Nikola; Tomaš, Renato; Požar, Josip; Barišić, Dajana; Bregović, Nikola; Pičuljan, Katarina; Frkanec, Leo; Tomišić, Vladislav
Synthesis and complexation properties of calix[4]arene glycoconjugates // 25th CROATIAN MEETING OF CHEMISTS AND CHEMICAL ENGINEERS
Poreč, Hrvatska, 2017. (poster, domaća recenzija, sažetak, znanstveni)


Naslov
Synthesis and complexation properties of calix[4]arene glycoconjugates

Autori
Cindro, Nikola ; Tomaš, Renato ; Požar, Josip ; Barišić, Dajana ; Bregović, Nikola ; Pičuljan, Katarina ; Frkanec, Leo ; Tomišić, Vladislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
25th CROATIAN MEETING OF CHEMISTS AND CHEMICAL ENGINEERS

Mjesto i datum
Poreč, Hrvatska, 19-22 April 2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Calixarene ; complexation ; glycoconjugate

Sažetak
Calixarenes are a class of supramolecular cavitands that can be easily functionalized to give receptors for ionic and neutral species. In many papers published so far their use has been tested in a wide range of applications, from simple host-guest interactions to biomimetics and catalysis. Structural evolution of these compounds has led to more selective receptors with improved physico-chemical properties. Most of the synthesized calixarene ionic receptors are not sufficiently soluble in water which makes their use quite limited [1]. Water-soluble calixarenes usually own this property to the introduced easily-ionized sulfonic groups. In the scope of this work novel neutral and water-soluble ligands 1–3 (Figure 1) were designed and prepared, and their complexation with alkali-metal cations was investigated. Glucose was embedded in the structure as hydrophilic domain whereas secondary and tertiary amides served as cation- binding sites. The latter motifs were used since the calixarene derivatives comprising such groups were previously proven to form highly stable complexes [2]. Complexation reactions with alkali-metal cations were studied in water, methanol, and formamide thus giving insight into the solvation as well as intra- and intermolecular hydrogen bonds effects. Several techniques were used, such as UV spectrophotometry, isothermal titration calorimetry and NMR spectroscopy.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2014-09-7309 - razvoj supramolekulskih receptora kationa i aniona (Vladislav Tomišić, )

Ustanove
Prirodoslovno-matematički fakultet, Zagreb