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Pregled bibliografske jedinice broj: 878045

Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience


Kovačević, Maja; Lukinović-Škudar, Vesna; Maričić, Goran; Krnjević-Pezić, Gordana; Stanimirović, Andrija
Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience // Acta dermatovenerologica Alpina, Pannonica et Adriatica, 23 (2014), 4; 75-78 (međunarodna recenzija, članak, znanstveni)


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Naslov
Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience

Autori
Kovačević, Maja ; Lukinović-Škudar, Vesna ; Maričić, Goran ; Krnjević-Pezić, Gordana ; Stanimirović, Andrija

Izvornik
Acta dermatovenerologica Alpina, Pannonica et Adriatica (1318-4458) 23 (2014), 4; 75-78

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
topical, propranolol, cream, superficial, infantile, hemangiomas

Sažetak
The clinical efficacy and safety profile of propranolol 1% cream in treatment of superficial infantile hemangiomas (IHs) were determined in a preliminary randomized group of eight infants. Five boys and three girls, 3 to 12 months old, with an IHs superficial capillary type on the forehead, posterior side of the neck, forearm, abdomen, or posterior side of the trunk were examined at our outpatient clinic between 2011 and 2014. Topical propranolol was applied twice daily for 10 months with clinical evaluation and photographic documentation performed every 1 to 2 months. Size, texture, and color changes were monitored. Therapeutic efficacy was evaluated using the Archauer system: Grade I (bad) reduction in size < 25%, Grade II (medium) reduction between 26% and 50%, Grade III (good) reduction between 51% and 75%, and Grade IV (excellent) reduction > 75%. The majority of hemangiomas treated, 62.5%, achieved Grade IV. A Grade III outcome was noticed in one patient with an IH (12.5%) and Grade II in 25% of patients with IHs on the abdomen. The treatment was well tolerated without side effects, which indicates that topical application of 1% propranolol is a safe, effective, and cheap therapeutic option for treating superficial IHs.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Zdravstveno veleučilište, Zagreb

Citiraj ovu publikaciju

Kovačević, Maja; Lukinović-Škudar, Vesna; Maričić, Goran; Krnjević-Pezić, Gordana; Stanimirović, Andrija
Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience // Acta dermatovenerologica Alpina, Pannonica et Adriatica, 23 (2014), 4; 75-78 (međunarodna recenzija, članak, znanstveni)
Kovačević, M., Lukinović-Škudar, V., Maričić, G., Krnjević-Pezić, G. & Stanimirović, A. (2014) Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience. Acta dermatovenerologica Alpina, Pannonica et Adriatica, 23 (4), 75-78.
@article{article, year = {2014}, pages = {75-78}, keywords = {topical, propranolol, cream, superficial, infantile, hemangiomas}, journal = {Acta dermatovenerologica Alpina, Pannonica et Adriatica}, volume = {23}, number = {4}, issn = {1318-4458}, title = {Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience}, keyword = {topical, propranolol, cream, superficial, infantile, hemangiomas} }
@article{article, year = {2014}, pages = {75-78}, keywords = {topical, propranolol, cream, superficial, infantile, hemangiomas}, journal = {Acta dermatovenerologica Alpina, Pannonica et Adriatica}, volume = {23}, number = {4}, issn = {1318-4458}, title = {Topical propranolol cream in treatment of superficial infantile hemangiomas: review of literature and 4 years clinical experience}, keyword = {topical, propranolol, cream, superficial, infantile, hemangiomas} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)
  • Scopus
  • MEDLINE





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