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Pregled bibliografske jedinice broj: 876371

Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging


Weitner, Tin; Batinić-Haberle, Ines
Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging // ADMET & DMPK, 2 (2014), 3; 185-190 doi:10.5599/admet.2.3.123 (recenziran, članak, znanstveni)


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Naslov
Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging

Autori
Weitner, Tin ; Batinić-Haberle, Ines

Izvornik
ADMET & DMPK (1848-7718) 2 (2014), 3; 185-190

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
metalloporphyrins ; oxidative stress ; superoxide ; peroxynitrite ; cyclic voltammetry

Sažetak
Manganese ortho tetrakis(N-n- butoxyethylpyridinium-2-yl)porphyrin, MnTnBuOE- 2-PyP5+, is a third-generation redox-active compound currently undergoing preclinical exploration. This work is intended to complement the already extensive research of its chemical and biological properties by a simple electrochemical study. The thermodynamic parameters related to the Mn(IV) porphyrin species of MnTnBuOE-2-PyP5+ determined in this work support its observed reactivity as an efficient scavenger of peroxynitrite. The corresponding driving forces for the possible single-electron or two-electron reductions of ONOO- have been estimated as well.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Ustanove
Farmaceutsko-biokemijski fakultet, Zagreb

Profili:

Avatar Url Ines Batinić-Haberle (autor)

Avatar Url Tin Weitner (autor)

Citiraj ovu publikaciju

Weitner, Tin; Batinić-Haberle, Ines
Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging // ADMET & DMPK, 2 (2014), 3; 185-190 doi:10.5599/admet.2.3.123 (recenziran, članak, znanstveni)
Weitner, T. & Batinić-Haberle, I. (2014) Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging. ADMET & DMPK, 2 (3), 185-190 doi:10.5599/admet.2.3.123.
@article{article, year = {2014}, pages = {185-190}, DOI = {10.5599/admet.2.3.123}, keywords = {metalloporphyrins, oxidative stress, superoxide, peroxynitrite, cyclic voltammetry}, journal = {ADMET and DMPK}, doi = {10.5599/admet.2.3.123}, volume = {2}, number = {3}, issn = {1848-7718}, title = {Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging}, keyword = {metalloporphyrins, oxidative stress, superoxide, peroxynitrite, cyclic voltammetry} }

Časopis indeksira:


  • Scopus


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  • CA Search (Chemical Abstracts)


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