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Pregled bibliografske jedinice broj: 874173

Novel DNA/RNA-targeting amino acid beacon for the versatile incorporation at any position within the peptide backbone


Šmidlehner, Tamara; Piantanida, Ivo
Novel DNA/RNA-targeting amino acid beacon for the versatile incorporation at any position within the peptide backbone // Amino acids (Wien), 49 (2017), 8; 1381-1388 doi:10.1007/s00726-017-2438-x (međunarodna recenzija, članak, znanstveni)


Naslov
Novel DNA/RNA-targeting amino acid beacon for the versatile incorporation at any position within the peptide backbone

Autori
Šmidlehner, Tamara ; Piantanida, Ivo

Izvornik
Amino acids (Wien) (0939-4451) 49 (2017), 8; 1381-1388

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Fluorescent amino acid ; one-pot synthesis ; DNA/RNA recognition ; fluorescence ; CD

Sažetak
One-pot tandem synthesis was for the first time applied to attach fluorophore to the amino acid side chain, yielding amino acid ready for peptide coupling at the N-terminus, and also upon activation at the C-terminus. Two new compounds differing only in fluorophore-linker length showed exceptional fluorimetric and CD recognition between DS-RNA and DS-DNA, thus being promising beacons for versatile peptide incorporation.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2013-11-1477 - Višenamjensko očitavanje DNA / RNA sekundarne strukture molekularnim kemijskim senzorima (Ivo Piantanida, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Scopus


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