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Pregled bibliografske jedinice broj: 87416

Preliminary study of cytogenetic damage in personnel exposed to cytogenetic damage


Rozgaj, Ružica; Kašuba, Vilena; Jazbec, Anamarija
Preliminary study of cytogenetic damage in personnel exposed to cytogenetic damage // Mutagenesis, 16 (2001), 2; 139-143 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 87416 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Preliminary study of cytogenetic damage in personnel exposed to cytogenetic damage
(Preliminary study of cytogenetic damage in personnel exposed to anesthetic gases)

Autori
Rozgaj, Ružica ; Kašuba, Vilena ; Jazbec, Anamarija

Izvornik
Mutagenesis (0267-8357) 16 (2001), 2; 139-143

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Preliminary study; cytogenetic damage; cytogenetic damage

Sažetak
Occupational exposure to anesthetic gases is associated with various adverse health effects. Genetic material has been shown to be a sensitive target of numerous harmful agents. The aim of this study was to examine whether chromosomal damage could serve to indicate exposure to anesthetics. A group of 43 hospital workers of three professions (anesthesiologists, technicians and operating room nurses) and 26 control subjects were examined for chromosome aberrations, sister chromatid exchanges and micronucleus frequency, The exposed groups matched in duration of exposure to anesthetics, but not in age. An equal ratio between women and men was possible in all groups except nurses. Likewise, the ratio between smokers and non-smokers was also not comparable. An increase in chromosome damage was found in all exposed groups. While the increase in sister chromatid exchange frequency was not significant, chromosome aberrations and micronucleus frequency increased significantly, showing higher rates in women, The results suggest that the micronucleus test is the most sensitive indicator of changes caused by anesthetic gases. The observed difference between sexes with respect to exposure risk call for further, targeted investigations.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
0022019
00220107

Ustanove
Institut za medicinska istraživanja i medicinu rada, Zagreb

Profili:

Avatar Url Ružica Rozgaj (autor)

Avatar Url Vilena Kašuba (autor)

Avatar Url Anamarija Jazbec (autor)

Citiraj ovu publikaciju

Rozgaj, Ružica; Kašuba, Vilena; Jazbec, Anamarija
Preliminary study of cytogenetic damage in personnel exposed to cytogenetic damage // Mutagenesis, 16 (2001), 2; 139-143 (međunarodna recenzija, članak, znanstveni)
Rozgaj, R., Kašuba, V. & Jazbec, A. (2001) Preliminary study of cytogenetic damage in personnel exposed to cytogenetic damage. Mutagenesis, 16 (2), 139-143.
@article{article, year = {2001}, pages = {139-143}, keywords = {Preliminary study, cytogenetic damage, cytogenetic damage}, journal = {Mutagenesis}, volume = {16}, number = {2}, issn = {0267-8357}, title = {Preliminary study of cytogenetic damage in personnel exposed to anesthetic gases}, keyword = {Preliminary study, cytogenetic damage, cytogenetic damage} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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