A meta-analysis reveals complex regulatory properties at Taf14-repressed genes (CROSBI ID 238875)
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Podaci o odgovornosti
Nemet, Josipa ; Vidan, Nikolina ; Sopta, Marija Mary
engleski
A meta-analysis reveals complex regulatory properties at Taf14-repressed genes
Regulation of gene transcription in response to stress is central to a cell's ability to cope with environmental challenges. Taf14 is a YEATS domain protein in S.cerevisiae that physically associates with several transcriptionally relevant multisubunit complexes including the general transcription factors TFIID and TFIIF and the chromatin-modifying complexes SWI/SNF, INO80, RSC and NuA3. TAF14 deletion strains are sensitive to a variety of stresses suggesting that it plays a role in the transcriptional stress response.
Meta-analysis ; Saccharomyces cerevisiae ; Transcription regulation
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