engleski

How to asses the skin barrier function?

Skin barrier function can be assessed in vivo in non-invasive manner by measuring trans-epidermal water loss. Measurement of a trans-epidermal water loss is more common in clinical settings due to simplicity. Common in vivo methods for determination of dermal absorption include measurement of parent chemical or its metabolite in blood and/or excreta (urin) and exhaled air, microdialysis and tape stripping of the stratum corneum. These methods will be discussed in detail.

skin barrier function ; skin absorption: diffusion: biological monitoring ; trans-epidermal water loss

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