engleski

Smoking behaviors and lung cancer epidemiology: a cohort study

Lung cancer is the most common cancer in the world. According to the latest available data, in year 2012 Croatia was among 20 countries with the highest incidence of lung cancer. Although tobacco smoking is a proven cause of lung cancer, recent data show that more than one quarter of adult inhabitants of Croatia are every day smokers. The purpose of this study was to present epidemiology and treatment modalities of lung cancer in the Department for mediastinal tumors, Clinic for lung diseases Jordanovac, and to make a comparison with available data from Croatia and the rest of the World. Subjects and methods: Study cohort included 212 newly diagnosed lung cancer patients who had referred to our Department from January of 2012 until December of 2012. Features such as age, gender, cytology and histology of the tumor, stage at diagnosis and applied therapy were evaluated prospectively. Approximately two-thirds of all newly diagnosed lung cancers occurred in men. Of all study cohort 12.3% were diagnosed with small cell lung cancer (SCLC) and 87.7% were diagnosed with non-small cell lung cancer (NSCLC). The majority of patients diagnosed with NSCLC had adenocarcinoma (47.9%), followed by squamous cell carcinoma (33.9%) and large cell carcinoma (15%). Only a small number of patients diagnosed and treated for lung cancer in our Department have never smoked tobacco. Majority of those patients were women and the most common histological type found was adenocarcinoma. The number of patients who had potentially operable disease at presentation was around 10%. That is why, in most cases, therapeutic options were confined to palliative chemotherapy or radiotherapy. Attention should be directed to the earlier detection of lung cancer patients, which could provide better treatment options and improve overall survival.

lung cancer ; epidemiology ; tobacco smoking ; lung cancer treatment

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