Organocatalytic Asymmetric Transformations of 3- Substituted 3-Hydroxyisoindolinones (CROSBI ID 238595)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Glavač, Danijel ; Gredičak, Matija
engleski
Organocatalytic Asymmetric Transformations of 3- Substituted 3-Hydroxyisoindolinones
This Account provides an overview of our group’s research in the field of asymmetric organocatalytic transformations generating chiral isoindolinone cores. We describe the synthesis of 3-substituted 3- hydroxyisoindolinones as starting materials for these transformations, comprising a wide range of functional groups, as well as their use in asymmetric transformations. We also discuss our efforts in the application of the developed methodology in the synthesis of a known HIV-1 inhibitor.
organocatalytic asymmetric transformations - 3-hydroxyisoindolinones - chiral Brønsted acid - isoindolinone core - organometallic addition - chiral N, S-acetals
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano